GGCX Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-59394

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Synthetic peptides corresponding to GGCX(gamma-glutamyl carboxylase) The peptide sequence was selected from the middle region of GGCX. Peptide sequence FLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGE. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for GGCX Antibody - BSA Free

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394] - Jurkat, Antibody Dilution: 1.0 ug/ml GGCX is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-59394] -

Immunohistochemistry-Paraffin: GGCX Antibody [NBP1-59394] - Formalin Fixed Paraffin; Embedded Tissue: Human Adult Liver; Observed Staining: Cytoplasm in hepatocytes, strong signal, wide tissue distribution; Primary Antibody Concentration: 1:100
Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394]

Western Blot: GGCX Antibody [NBP1-59394] - MCF-7 whole cell lysates, concentration 0.2-1 ug/ml.

Applications for GGCX Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GGCX

GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency.Gamma-glutamyl carboxylase accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP; MIM 112260) and bone matrix protein (MGP; MIM 154870).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Gamma-Glutamyl Carboxylase

Alternate Names

VKCFD1

Gene Symbol

GGCX

UniProt

Additional GGCX Products

Product Documents for GGCX Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GGCX Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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