Chemical Name: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione
Biological ActivityPlatelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of PAF-acether in the guinea-pig.
Desquand et al.
Inhibition by BN 52021 (ginkgolide B) of the binding of [3H]-platelet-activating factor to human neutrophil granulocytes.
Foldes-Filep et al.
The CNS effects of Ginkgo biloba extracts and ginkgolide B.
Maclennan et al.
Citation for Ginkgolide B
The citations listed below are publications that use Tocris products. Selected citations for Ginkgolide B include:
1 Citation: Showing 1 - 1
Protective effect of high concentration of BN52021 on retinal contusion in cat eyes.
Authors: Huang Et al.
Nat Neurosci 2015;15:50
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