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Ginkgolide B

1657 Datasheet / COA / SDS

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Ginkgolide B | CAS No. 15291-77-7 | Platelet-activating Factor Receptor Antagonists
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Description: PAF receptor antagonist
Alternative Names: BN 52021

Chemical Name: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione

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Biological Activity

Ginkgolide B is a platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo.

Technical Data

M.Wt:
424.4
Formula:
C20H24O10
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage:
Desiccate at +4°C
CAS No:
15291-77-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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