GPER/GPR30 Antibody - BSA Free

Novus Biologicals | Catalog # NLS4268

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all GPER/GPR30 Primary Antibodies »

Product Specifications

Immunogen

Synthetic 15 amino acid peptide from 2nd extracellular domain of human GPER/GPR30.

Epitope

2nd extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (93%), Mouse (87%), Rat (87%), Hamster (87%), Panda (87%), Equine (87%), Opossum (87%), Platypus (87%), Canine (80%), Bovine (80%), Turkey (80%), Zebra finch (80%), Chicken (80%).

Localization

Endoplasmic reticulum - multi-pass membrane protein.

Specificity

Human GPR30. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for GPER/GPR30 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPER/GPR30 Antibody - BSA Free [NLS4268]

Immunohistochemistry-Paraffin: GPER/GPR30 Antibody - BSA Free [NLS4268]

Immunohistochemistry-Paraffin: GPER/GPR30 Antibody [NLS4268] - Analysis of anti-GPR30 antibody with human skeletal muscle at dilution 5 - 7.5 ug/ml.
Immunohistochemistry-Paraffin: GPER/GPR30 Antibody - BSA Free [NLS4268]

Immunohistochemistry-Paraffin: GPER/GPR30 Antibody - BSA Free [NLS4268]

Immunohistochemistry-Paraffin: GPER/GPR30 Antibody [NLS4268] - Analysis of anti-GPR30 antibody with human, spleen.

Applications for GPER/GPR30 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunohistochemistry-Paraffin

5-7.5 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: GPER/GPR30

GPR30 is a transmembrane intracellular estrogen receptor (Revankar et al. 2005). Progestin inhibits growth in breast cancer cells through GPR30. GPR30 has been reported in brain, breast carcinoma, blood, bone marrow, CNS, heart, liver, lung, lymph node, placenta, and spleen. ESTs have been isolated from B-cell/lung/testis, brain, ganglion, heart/melanocyte/uterus, kidney, tonsil, liver/spleen, placenta, and prostate libraries. Ligands: Estrogen (Revankar et al. 2005). Caution: Rat GPR30 is also known as GPR41 and HIA-R

Long Name

G Protein-coupled Estrogen Receptor 1

Alternate Names

CEPR, CMKRL2, DRY12, FEG-1, GPCR-BR, GPR30, LERGU2, LyGPR

Entrez Gene IDs

2852 (Human)

Gene Symbol

GPER1

UniProt

Q99527

Additional GPER/GPR30 Products

Product Documents for GPER/GPR30 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for GPER/GPR30 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Obesity

Citations for GPER/GPR30 Antibody - BSA Free

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Protocols

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