hh GR 135531 (CAS 190277-13-5): R&D Systems
Catalog Number: 0896
Alternate Names: 5-MCA-NAT
Chemical Name: 5-Methoxycarbonylamino-N-acetyltryptamine
Biological Activity
Binds with high affinity to MT3 melatonin sites in hamster brain, and low affinity (and no efficacy) at MT1 and MT2 melatonin receptors and thus can be used to discriminate between the melatonin receptor subtypes.
Technical Data
  • M.Wt:
    275.31
  • Formula:
    C14H17N3O3
  • Solubility:
    Soluble to 100 mM in ethanol
  • Purity:
    >97%
  • Storage:
    Store at RT
  • CAS No:
    190277-13-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Melatonin receptors: are there multiple subtypes?
    Dubocovich
    TiPS, 1995;16:50
  2. Investigation into the contractile response of melatonin in the guinea-pig isolated proximal colon: the role of 5-HT4 and melatonin receptors.
    Lucchelli et al.
    Br.J.Pharmacol., 1997;121:1775
Citations:

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