Specific GABA uptake inhibitor. IC50
values are 14, 58, 119 and 1870 μ
M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
Borden et al.
Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds.
Krogsgaard-Larsen et al.
The citations listed below are publications that use Tocris products. Selected citations for Guvacine hydrochloride include:
Showing Results 1 - 1 of 1