Catalog Number: 0234
Chemical Name: 1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride
Biological Activity
Specific GABA uptake inhibitor. IC50 values are 14, 58, 119 and 1870 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
    Borden et al.
    Eur.J.Pharmacol., 1994;269:219
  2. Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds.
    Krogsgaard-Larsen et al.
    J.Neurochem., 1978;30:1377

The citations listed below are publications that use Tocris products. Selected citations for Guvacine hydrochloride include:

Showing Results 1 - 1 of 1

  1. Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).
    Authors: Edwards Et al.
    Biochim Biophys Acta
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information