Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK1
values are 0.175 and 560 nM for NK1
receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro
and is antihypertensive in vivo
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Pharmacological profile of the novel mammalian tachykinin hemokinin 1.
Bellucci et al.
Hemokinin 1 is a full agonist at the substance P receptor.
Morteau et al.
Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis.
Zhang et al.