Catalog Number: 1535
Alternate Names: HK-1, HEK-1
Biological Activity
Novel mammalian endogenous peptide, homolog of substance P, that is a high affinity and selective agonist at the tachykinin NK1 receptor (Ki values are 0.175 and 560 nM for NK1 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
Technical Data
  • M.Wt:
    1413.66
  • Formula:
    C61H100N22O15S
  • Sequence:
    RSRTRQFYGLM

    (Modifications: Met-11 = C-terminal amide)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    208041-90-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pharmacological profile of the novel mammalian tachykinin hemokinin 1.
    Bellucci et al.
    Br.J.Pharmacol., 2002;135:266
  2. Hemokinin 1 is a full agonist at the substance P receptor.
    Morteau et al.
    Nat.Immunol., 2001;2:1088
  3. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis.
    Zhang et al.
    Nat.Immunol., 2000;1:392

Have you used Hemokinin 1 (mouse)?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information