Catalog Number: 5824
Chemical Name: 4-[6-(4-Methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]phenol trihydrochloride
Biological Activity
Fluorescent dye. Binds the minor groove of DNA at A and T rich regions. Can be used as indicator of apoptosis.
Technical Data
  • M.Wt:
    533.88
  • Formula:
    C25H24N6O.3HCl
  • Solubility:
    Soluble to 20 mM in DMSO and to 100 mM in water
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    23491-45-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.
    Oberhammer et al.
    EMBO J., 1993;12:3679
  2. Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex.
    Jin and Breslauer
    Proc.Natl.Acad.Sci.U.S.A., 1988;85:8939
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