HT 8-oxo-dG ELISA Kit II

For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples
Catalog # Availability Size / Price Qty
4380-096-K
4380-192-K
Product Details
Citations (10)
FAQs
Reviews (3)

HT 8-oxo-dG ELISA Kit II Summary

Quantifies 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.

Key Benefits

• Colorimetric, non-radioactive format
• High throughput 96 strip wells
• Dynamic range from 3.13 nM to 200 nM (0.89 ng/mL to 56.7 ng/mL)
• Sensitivity at 2 nM (0.57 ng/mL) 8-OHdG

Product Specifications

For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.

Other Resources

4380-096-k_calculation_worksheet

Kit Contents

• 8-OHdG Standard, 20 µM
• 8-OHdG Monoclonal Antibody
• Goat anti-Mouse IgG-HRP
• DNase I (5 Units/µl)
• Alkaline Phosphatase (1 Unit/µl)
• Assay Dilutent
• 100X Cations
• Pre-coated 96-stripwell plate
• TACS-Sapphire

Specifications

Shipping Conditions
The components for this kit may require different storage/shipping temperatures and may arrive in separate packaging. Upon receipt, store products immediately at the temperature recommended on the product labels.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-species

Limitations

For research use only. Not for diagnositic use.

Product Datasheets

Citations for HT 8-oxo-dG ELISA Kit II

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

10 Citations: Showing 1 - 10
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  1. Impairment of Pol &beta-related DNA Base-excision Repair Leads to Ovarian Aging in Mice
    Authors: K Hua, L Wang, J Sun, N Zhou, Y Zhang, F Ji, L Jing, Y Yang, W Xia, Z Hu, F Pan, X Chen, B Yao, Z Guo
    Aging (Albany NY), 2020;12(0):.  2020
  2. Urinary Biomarkers of Inflammation and Oxidative Stress Are Elevated in Obese Children and Correlate with a Marker of Endothelial Dysfunction
    Authors: V Selvaraju, P Ayine, M Fadamiro, JR Babu, M Brown, T Geetha
    Oxid Med Cell Longev, 2019;2019(0):9604740.  2019
  3. CoPP-Induced-Induced HO-1 Overexpression Alleviates Photoreceptor Degeneration With Rapid Dynamics: A Therapeutic Molecular Against Retinopathy
    Authors: Y Tao, L Cai, D Zhou, C Wang, Z Ma, X Dong, G Peng
    Invest. Ophthalmol. Vis. Sci., 2019;60(15):5080-5094.  2019
  4. NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease.
    Authors: Weyemi, Urbain, Redon, Christop, Aziz, Towqir, Choudhuri, Rohini, Maeda, Daisuke, Parekh, Palak R, Bonner, Michael, Arbiser, Jack L, Bonner, William
    Proc Natl Acad Sci U S A, 2015;112(7):2121-6.  2015
  5. Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats.
    Authors: Klarich D, Penprase J, Cintora P, Medrano O, Erwin D, Brasser S, Hong M
    Alcohol, 0;61(0):25-31.  0
  6. Smg1 haploinsufficiency predisposes to tumor formation and inflammation.
    Authors: Roberts T, Ho U, Luff J, Lee C, Apte S, MacDonald K, Raggat L, Pettit A, Morrow C, Waters M, Chen P, Woods R, Thomas G, St Pierre L, Farah C, Clarke R, Brown J, Lavin M
    Proc Natl Acad Sci U S A, 0;110(4):E285-94.  0
  7. SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation.
    Authors: Kim J, Mizokami A, Shin M, Izumi K, Konaka H, Kadono Y, Kitagawa Y, Keller E, Zhang J, Namiki M
    Anticancer Res, 0;34(6):2821-31.  0
  8. Role of Bacillus subtilis error prevention oxidized guanine system in counteracting hexavalent chromium-promoted oxidative DNA damage.
    Authors: Santos-Escobar F, Gutierrez-Corona J, Pedraza-Reyes M
    Appl Environ Microbiol, 0;80(17):5493-502.  0
  9. Increased oxidative stress and cytokinesis-block micronucleus cytome assay parameters in pregnant women with gestational diabetes mellitus and gestational arterial hypertension.
    Authors: Toljic M, Egic A, Munjas J, Karadzov Orlic N, Milovanovic Z, Radenkovic A, Vuceljic J, Joksic I
    Reprod Toxicol, 0;71(0):55-62.  0
  10. Multi-walled carbon nanotubes: A cytotoxicity study in relation to functionalization, dose and dispersion.
    Authors: Zhou L, Forman H, Ge Y, Lunec J
    Toxicol In Vitro, 0;42(0):292-298.  0

FAQs

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Reviews for HT 8-oxo-dG ELISA Kit II

Average Rating: 4.3 (Based on 3 Reviews)

5 Star
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3 Star
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HT 8-oxo-dG ELISA Kit II
By Anonymous on 09/29/2020
Application:

Very sensitive assay that needs vigorous vortexing, but overall does produce good results.


HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 12/17/2018
Application:

HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 09/18/2018
Application: