HT 8-oxo-dG ELISA Kit II

For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples

Discontinued Product

4380-192-K has been discontinued.
View all 8-oxo-dG products.
Product Details
Citations (24)
Reviews (4)

HT 8-oxo-dG ELISA Kit II Summary

Quantifies 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.

Key Benefits

• Colorimetric, non-radioactive format
• High throughput 96 strip wells
• Dynamic range from 3.13 nM to 200 nM (0.89 ng/mL to 56.7 ng/mL)
• Sensitivity at 2 nM (0.57 ng/mL) 8-OHdG

Product Specifications

For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.

Other Resources


Kit Contents

• 8-OHdG Standard, 20 µM
• 8-OHdG Monoclonal Antibody
• Goat anti-Mouse IgG-HRP
• DNase I (5 Units/µl)
• Alkaline Phosphatase (1 Unit/µl)
• Assay Dilutent
• 100X Cations
• Pre-coated 96-stripwell plate
• TACS-Sapphire


Shipping Conditions
The components for this kit may require different storage/shipping temperatures and may arrive in separate packaging. Upon receipt, store products immediately at the temperature recommended on the product labels.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.


For research use only. Not for diagnostic use.

Product Datasheets

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Citations for HT 8-oxo-dG ELISA Kit II

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

24 Citations: Showing 1 - 10
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  1. Acetyl Tributyl Citrate Exposure at Seemingly Safe Concentrations Induces Adverse Effects in Different Genders of Type 2 Diabetes Mice, Especially Brain Tissue
    Authors: Zhang, Y;Zhang, Z;Zhu, S;Liu, L;Liu, X;Yang, X;
    Toxics  2023-10-23
  2. Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models
    Authors: Rahman, M;Upadhyay, S;Ganguly, K;Introna, M;Ji, J;Boman, C;Muala, A;Blomberg, A;Sandström, T;Palmberg, L;
    Toxics  2023-06-14
  3. A coffee enriched with guarana, selenium, and l-carnitine (GSC) has nutrigenomic effects on oxi-inflammatory markers of relapsing-remitting multiple sclerosis patients: A pilot study
    Authors: CF Teixeira, VF Azzolin, G Rodrigues, BO Turra, AO Alves, ACM Bressanim, LEL Canton, AC Vieira Dos, MH Mastella, F Barbisan, EE Ribeiro, T Duarte, MMMF Duarte, NCA Bonotto, DK Sato, IBM da Cruz
    Multiple sclerosis and related disorders, 2023-01-13;71(0):104515.  2023-01-13
  4. In utero arsenic exposure increases DNA damage and gene expression changes in umbilical cord mesenchymal stem cells (UC-MSCs) from newborns as well as in UC-MSC differentiated hepatocytes
    Authors: S Kantisin, K Chaisatra, P Hunsonti, V Parnlob, P Navasumrit, M Ruchirawat
    Toxicology reports, 2022-09-07;9(0):1728-1741.  2022-09-07
  5. A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population
    Authors: M Wu, C Ye, H Li, X Yang, S Zhu, F Zhou, Y Hao, S Chen, S Jiang
    BioMed Research International, 2022-08-18;2022(0):8629680.  2022-08-18
  6. Monitoring DNA polymerase beta mitochondrial localization and dynamics
    Authors: JK Horton, AK Janoshazi, CA Nadalutti, ML Zhao, DF Stefanick, SH Wilson
    DNA repair, 2022-06-11;116(0):103357.  2022-06-11
  7. Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair
    Authors: CC Gruber, VMP Babu, K Livingston, H Joisher, GC Walker
    MBio, 2022-02-08;0(0):e0375621.  2022-02-08
  8. Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
    Authors: P Carotenuto, F Amato, A Lampis, C Rae, S Hedayat, MC Previdi, D Zito, M Raj, V Guzzardo, F Sclafani, A Lanese, C Parisi, C Vicentini, I Said-Hunti, JC Hahne, A Hallsworth, V Kirkin, K Young, R Begum, A Wotherspoo, K Kouvelakis, SX Azevedo, V Michalarea, R Upstill-Go, S Rao, D Watkins, N Starling, A Sadanandam, DK Chang, AV Biankin, NB Jamieson, A Scarpa, D Cunningham, I Chau, P Workman, M Fassan, N Valeri, C Braconi
    Nature Communications, 2021-11-18;12(1):6738.  2021-11-18
  9. AKR1C1 alleviates LPS?induced ALI in mice by activating the JAK2/STAT3 signaling pathway
    Authors: X Wang, B Yang, Y Li, J Luo, Y Wang
    Molecular Medicine Reports, 2021-09-30;24(6):.  2021-09-30
  10. Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in�vivo cell engraftment
    Authors: AM Pettinato, D Yoo, J VanOudenho, YS Chen, R Cohn, FA Ladha, X Yang, K Thakar, R Romano, N Legere, E Meredith, P Robson, M Regnier, JL Cotney, CE Murry, JT Hinson
    Cell Reports, 2021-05-04;35(5):109088.  2021-05-04
  11. Diagnostic and prognostic ability of salivary MMP-9 for oral squamous cell carcinoma: A pre-/post-surgery case and matched control study
    Authors: YJ Shin, H Vu, JH Lee, HD Kim
    PLoS ONE, 2021-03-18;16(3):e0248167.  2021-03-18
  12. Impairment of Pol &beta-related DNA Base-excision Repair Leads to Ovarian Aging in Mice
    Authors: K Hua, L Wang, J Sun, N Zhou, Y Zhang, F Ji, L Jing, Y Yang, W Xia, Z Hu, F Pan, X Chen, B Yao, Z Guo
    Aging (Albany NY), 2020-11-20;12(0):.  2020-11-20
  13. Indole-6-Carboxaldehyde Isolated from Sargassum thunbergii (Mertens) Kuntze Prevents Oxidative Stress-Induced Cellular Damage in V79-4 Chinese Hamster Lung Fibroblasts through the Activation of the Nrf2/HO-1 Signaling Pathway
    Authors: SO Kim, YH Choi
    Cell Physiol Biochem, 2020-10-01;54(5):959-974.  2020-10-01
  14. Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression
    Authors: W Huang, H Tang, F Wen, X Lu, Q Li, P Shu
    BMC Complement Med Ther, 2020-06-26;20(1):196.  2020-06-26
  15. CoPP-Induced-Induced HO-1 Overexpression Alleviates Photoreceptor Degeneration With Rapid Dynamics: A Therapeutic Molecular Against Retinopathy
    Authors: Y Tao, L Cai, D Zhou, C Wang, Z Ma, X Dong, G Peng
    Invest. Ophthalmol. Vis. Sci., 2019-12-02;60(15):5080-5094.  2019-12-02
  16. Urinary Biomarkers of Inflammation and Oxidative Stress Are Elevated in Obese Children and Correlate with a Marker of Endothelial Dysfunction
    Authors: V Selvaraju, P Ayine, M Fadamiro, JR Babu, M Brown, T Geetha
    Oxid Med Cell Longev, 2019-10-16;2019(0):9604740.  2019-10-16
  17. Blood leukocyte LINE-1 hypomethylation and oxidative stress in knee osteoarthritis
    Authors: N Teerawatta, W Udomsinpra, S Ngarmukos, A Tanavalee, S Honsawek
    Heliyon, 2019-05-24;5(5):e01774.  2019-05-24
  18. Multi-walled carbon nanotubes: A cytotoxicity study in relation to functionalization, dose and dispersion.
    Authors: Zhou L, Forman H, Ge Y, Lunec J
    Toxicol In Vitro, 2017-05-05;42(0):292-298.  2017-05-05
  19. Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats.
    Authors: Klarich D, Penprase J, Cintora P, Medrano O, Erwin D, Brasser S, Hong M
    Alcohol, 2017-04-18;61(0):25-31.  2017-04-18
  20. Increased oxidative stress and cytokinesis-block micronucleus cytome assay parameters in pregnant women with gestational diabetes mellitus and gestational arterial hypertension.
    Authors: Toljic M, Egic A, Munjas J, Karadzov Orlic N, Milovanovic Z, Radenkovic A, Vuceljic J, Joksic I
    Reprod Toxicol, 2017-04-08;71(0):55-62.  2017-04-08
  21. NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease.
    Authors: Weyemi, Urbain, Redon, Christop, Aziz, Towqir, Choudhuri, Rohini, Maeda, Daisuke, Parekh, Palak R, Bonner, Michael, Arbiser, Jack L, Bonner, William
    Proc Natl Acad Sci U S A, 2015-02-02;112(7):2121-6.  2015-02-02
  22. Role of Bacillus subtilis error prevention oxidized guanine system in counteracting hexavalent chromium-promoted oxidative DNA damage.
    Authors: Santos-Escobar F, Gutierrez-Corona J, Pedraza-Reyes M
    Appl Environ Microbiol, 2014-06-27;80(17):5493-502.  2014-06-27
  23. SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation.
    Authors: Kim J, Mizokami A, Shin M, Izumi K, Konaka H, Kadono Y, Kitagawa Y, Keller E, Zhang J, Namiki M
    Anticancer Res, 2014-06-01;34(6):2821-31.  2014-06-01
  24. Smg1 haploinsufficiency predisposes to tumor formation and inflammation.
    Authors: Roberts T, Ho U, Luff J, Lee C, Apte S, MacDonald K, Raggat L, Pettit A, Morrow C, Waters M, Chen P, Woods R, Thomas G, St Pierre L, Farah C, Clarke R, Brown J, Lavin M
    Proc Natl Acad Sci U S A, 2012-12-31;110(4):E285-94.  2012-12-31


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Reviews for HT 8-oxo-dG ELISA Kit II

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HT 8-oxo-dG ELISA Kit II
By Anonymous on 09/06/2023

Catalog No. 4380-096-P (Contains 1 plate only)
LOT : P324064

Sample type being tested: Human Plasma

The standard curve came out well.
However, our plasma samples were diluted 1/10 suggested by the kit. Our OD values were out of range.

If you have enough plates, I would suggest to perform a standardization run, to determine optimal dilution for your samples first.

HT 8-oxo-dG ELISA Kit II
By Lindsie Morin on 09/29/2020

Very sensitive assay that needs vigorous vortexing, but overall does produce good results.

HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 12/17/2018

HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 09/18/2018