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HT 8-oxo-dG ELISA Kit II

4380-192-K 18 Citations 3 Reviews Datasheet / COA / SDS
For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples
Catalog # Availability Size / Price Qty
4380-096-K
4380-192-K
Product Details
Citations (18)
FAQs
Reviews (3)
Summary Product Datasheets

HT 8-oxo-dG ELISA Kit II Summary

Quantifies 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.
 

Key Benefits

• Colorimetric, non-radioactive format
• High throughput 96 strip wells
• Dynamic range from 3.13 nM to 200 nM (0.89 ng/mL to 56.7 ng/mL)
• Sensitivity at 2 nM (0.57 ng/mL) 8-OHdG

Product Specifications

For the detection and quantitation of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA, plasma, urine and saliva samples.

Other Resources

4380-096-k_calculation_worksheet

Kit Contents

• 8-OHdG Standard, 20 µM
• 8-OHdG Monoclonal Antibody
• Goat anti-Mouse IgG-HRP
• DNase I (5 Units/µl)
• Alkaline Phosphatase (1 Unit/µl)
• Assay Dilutent
• 100X Cations
• Pre-coated 96-stripwell plate
• TACS-Sapphire

Specifications

Shipping Conditions
The components for this kit may require different storage/shipping temperatures and may arrive in separate packaging. Upon receipt, store products immediately at the temperature recommended on the product labels.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Multi-species

Limitations

For research use only. Not for diagnostic use.

Product Datasheets

Product Datasheet
COA
SDS

Citations for HT 8-oxo-dG ELISA Kit II

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

18 Citations: Showing 1 - 10
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  1. Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair
    Authors: CC Gruber, VMP Babu, K Livingston, H Joisher, GC Walker
    MBio, 2022;0(0):e0375621.  2022
  2. Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in�vivo cell engraftment
    Authors: AM Pettinato, D Yoo, J VanOudenho, YS Chen, R Cohn, FA Ladha, X Yang, K Thakar, R Romano, N Legere, E Meredith, P Robson, M Regnier, JL Cotney, CE Murry, JT Hinson
    Cell Reports, 2021;35(5):109088.  2021
  3. Diagnostic and prognostic ability of salivary MMP-9 for oral squamous cell carcinoma: A pre-/post-surgery case and matched control study
    Authors: YJ Shin, H Vu, JH Lee, HD Kim
    PLoS ONE, 2021;16(3):e0248167.  2021
  4. Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
    Authors: P Carotenuto, F Amato, A Lampis, C Rae, S Hedayat, MC Previdi, D Zito, M Raj, V Guzzardo, F Sclafani, A Lanese, C Parisi, C Vicentini, I Said-Hunti, JC Hahne, A Hallsworth, V Kirkin, K Young, R Begum, A Wotherspoo, K Kouvelakis, SX Azevedo, V Michalarea, R Upstill-Go, S Rao, D Watkins, N Starling, A Sadanandam, DK Chang, AV Biankin, NB Jamieson, A Scarpa, D Cunningham, I Chau, P Workman, M Fassan, N Valeri, C Braconi
    Nature Communications, 2021;12(1):6738.  2021
  5. AKR1C1 alleviates LPS?induced ALI in mice by activating the JAK2/STAT3 signaling pathway
    Authors: X Wang, B Yang, Y Li, J Luo, Y Wang
    Molecular Medicine Reports, 2021;24(6):.  2021
  6. Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression
    Authors: W Huang, H Tang, F Wen, X Lu, Q Li, P Shu
    BMC Complement Med Ther, 2020;20(1):196.  2020
  7. Indole-6-Carboxaldehyde Isolated from Sargassum thunbergii (Mertens) Kuntze Prevents Oxidative Stress-Induced Cellular Damage in V79-4 Chinese Hamster Lung Fibroblasts through the Activation of the Nrf2/HO-1 Signaling Pathway
    Authors: SO Kim, YH Choi
    Cell Physiol Biochem, 2020;54(5):959-974.  2020
  8. Impairment of Pol &beta-related DNA Base-excision Repair Leads to Ovarian Aging in Mice
    Authors: K Hua, L Wang, J Sun, N Zhou, Y Zhang, F Ji, L Jing, Y Yang, W Xia, Z Hu, F Pan, X Chen, B Yao, Z Guo
    Aging (Albany NY), 2020;12(0):.  2020
  9. Urinary Biomarkers of Inflammation and Oxidative Stress Are Elevated in Obese Children and Correlate with a Marker of Endothelial Dysfunction
    Authors: V Selvaraju, P Ayine, M Fadamiro, JR Babu, M Brown, T Geetha
    Oxid Med Cell Longev, 2019;2019(0):9604740.  2019
  10. CoPP-Induced-Induced HO-1 Overexpression Alleviates Photoreceptor Degeneration With Rapid Dynamics: A Therapeutic Molecular Against Retinopathy
    Authors: Y Tao, L Cai, D Zhou, C Wang, Z Ma, X Dong, G Peng
    Invest. Ophthalmol. Vis. Sci., 2019;60(15):5080-5094.  2019
  11. Blood leukocyte LINE-1 hypomethylation and oxidative stress in knee osteoarthritis
    Authors: N Teerawatta, W Udomsinpra, S Ngarmukos, A Tanavalee, S Honsawek
    Heliyon, 2019;5(5):e01774.  2019
  12. NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease.
    Authors: Weyemi, Urbain, Redon, Christop, Aziz, Towqir, Choudhuri, Rohini, Maeda, Daisuke, Parekh, Palak R, Bonner, Michael, Arbiser, Jack L, Bonner, William
    Proc Natl Acad Sci U S A, 2015;112(7):2121-6.  2015
  13. Smg1 haploinsufficiency predisposes to tumor formation and inflammation.
    Authors: Roberts T, Ho U, Luff J, Lee C, Apte S, MacDonald K, Raggat L, Pettit A, Morrow C, Waters M, Chen P, Woods R, Thomas G, St Pierre L, Farah C, Clarke R, Brown J, Lavin M
    Proc Natl Acad Sci U S A, 0;110(4):E285-94.  0
  14. Multi-walled carbon nanotubes: A cytotoxicity study in relation to functionalization, dose and dispersion.
    Authors: Zhou L, Forman H, Ge Y, Lunec J
    Toxicol In Vitro, 0;42(0):292-298.  0
  15. Increased oxidative stress and cytokinesis-block micronucleus cytome assay parameters in pregnant women with gestational diabetes mellitus and gestational arterial hypertension.
    Authors: Toljic M, Egic A, Munjas J, Karadzov Orlic N, Milovanovic Z, Radenkovic A, Vuceljic J, Joksic I
    Reprod Toxicol, 0;71(0):55-62.  0
  16. Role of Bacillus subtilis error prevention oxidized guanine system in counteracting hexavalent chromium-promoted oxidative DNA damage.
    Authors: Santos-Escobar F, Gutierrez-Corona J, Pedraza-Reyes M
    Appl Environ Microbiol, 0;80(17):5493-502.  0
  17. SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation.
    Authors: Kim J, Mizokami A, Shin M, Izumi K, Konaka H, Kadono Y, Kitagawa Y, Keller E, Zhang J, Namiki M
    Anticancer Res, 0;34(6):2821-31.  0
  18. Effects of moderate alcohol consumption on gene expression related to colonic inflammation and antioxidant enzymes in rats.
    Authors: Klarich D, Penprase J, Cintora P, Medrano O, Erwin D, Brasser S, Hong M
    Alcohol, 0;61(0):25-31.  0

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Reviews for HT 8-oxo-dG ELISA Kit II

Average Rating: 4.3 (Based on 3 Reviews)

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HT 8-oxo-dG ELISA Kit II
By Lindsie Morin on 09/29/2020

Very sensitive assay that needs vigorous vortexing, but overall does produce good results.

HT 8-oxo-dG ELISA Kit II 4380-192-K
HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 12/17/2018
HT 8-oxo-dG ELISA II Kit, 2 Plates 4380-192-K
HT 8-oxo-dG ELISA II Kit, 2 Plates
By Anonymous on 09/18/2018
HT 8-oxo-dG ELISA II Kit, 2 Plates 4380-192-K