Human 5-HT2C APC-conjugated Antibody

  • Species Reactivity
  • Specificity
    Detects human 5-HT2C in direct ELISAs.
  • Source
    Monoclonal Mouse IgG2A Clone # 496214
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human 5-HT2C
    Accession # P28335
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of 5‑HT2C in HEK293 Human Cell Line Transfected with Human 5-HT2C and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP was stained with either (A) Mouse Anti-Human 5‑HT2C APC‑conjugated Monoclonal Antibody (Catalog # FAB5764A) or (B) Mouse IgG2A Allophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: 5-HT2C

5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled receptor #1 family. It binds serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5-HT2C ligation regulates mood, appetite, and motivation. 5-HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares 89% aa sequence identity with mouse and rat 5-HT2C.

  • Long Name:
    5-Hydroxytryptamine Receptor 2C
  • Entrez Gene IDs:
    3358 (Human); 15560 (Mouse); 25187 (Rat)
  • Alternate Names:
    5-HT1C; 5-HT-1C; 5HT2C; 5-HT-2C; 5-HT2C5-hydroxytryptamine receptor 1C; 5-HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; 5-hydroxytryptamine receptor 2C; HTR1C; HTR2C; serotonin 5-HT-2C receptor; Serotonin Receptor 2C
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2A APC-conjugated Antibody

Ctrl IC003A 1  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 3
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 1
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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