Human 5-HT2C PE-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB5764P-100
Human 5-HT2C PE-conjugated Antibody in Flow Cytometry
1 Image
Product Details
FAQs
Supplemental Products
Reviews

Human 5-HT2C PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human 5HT2C in direct ELISAs.
Source
Monoclonal Mouse IgG2A Clone # 496214
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
NS0 mouse myeloma cell line transfected with human 5HT2C
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of 5‑HT2C in HEK293 Human Cell Line Transfected with Human 5-HT2C and eGFP by Flow Cytometry. View Larger

Detection of 5‑HT2C in HEK293 Human Cell Line Transfected with Human 5-HT2C and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human 5-HT2C or (B) irrelevant protein, and eGFP was stained with Mouse Anti-Human 5-HT2C PE-conjugated Monoclonal Antibody (Catalog # FAB5764P) or (B) Mouse IgG2A PE Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: 5-HT2C

5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled receptor #1 family. It binds serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5-HT2C ligation regulates mood, appetite, and motivation. 5-HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares 89% aa sequence identity with mouse and rat 5-HT2C.

Long Name
5-Hydroxytryptamine Receptor 2C
Entrez Gene IDs
3358 (Human); 15560 (Mouse); 25187 (Rat)
Alternate Names
5-HT1C; 5-HT-1C; 5HT2C; 5-HT2C; 5-HT-2C; 5-HT2C5-hydroxytryptamine receptor 1C; 5-HTR2C; 5-hydroxytryptamine (serotonin) receptor 2C; 5-hydroxytryptamine receptor 2C; HTR1C; HTR2C; serotonin 5-HT-2C receptor; Serotonin Receptor 2C

Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human 5-HT2C PE-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human 5-HT2C PE-conjugated Antibody and earn rewards!

Have you used Human 5-HT2C PE-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review