Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Aminopeptidase LRAP/ERAP2 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Aminopeptidase LRAP/ERAP2
Ala56-Thr960
Accession # Q6P179

Specificity

Detects human Aminopeptidase LRAP/ERAP2 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Aminopeptidase LRAP/ERAP2 (Catalog # 3830-ZN)

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Aminopeptidase LRAP/ERAP2

Leukocyte-derived arginine aminopeptidase (LRAP) and endoplasmic reticulum-aminopeptidase 2 (ERAP2) are the two names given to the protein encoded by the LRAP gene (1, 2). Induced by interferon-gamma, LRAP is able to trim various MHC class I antigenic peptide precursors. It belongs to the oxytocinase subfamily of M1 aminopeptidases, which also includes aminopeptidases PILS/ARTS1/ERAP1 and LNPEP/PLAP (1, 3). In addition to antigen presentation, the members of this subfamily are also important in maintenance of pregnancy, memory retention, and blood pressure regulation (3).

References

  1. Tanioka, T. et al. (2003) J. Biol. Chem. 278:32275.
  2. Tanioka, T. et al. (2005) FEBS J. 272:916.
  3. Tsujimoto, M. and A. Hattori (2005) Biochim. Biophys. Acta 1751:9.

Long Name

Leukocyte-derived Arginine Aminopeptidase

Alternate Names

ERAP2

Entrez Gene IDs

64167 (Human)

Gene Symbol

ERAP2

UniProt

Q6P179

Additional Aminopeptidase LRAP/ERAP2 Products

Product Documents for Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody

For research use only

Related Research Areas

Metalloproteases and Regulators

Citations for Human Aminopeptidase LRAP/ERAP2 Biotinylated Antibody

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