Human Androgen R/NR3C4 (NP_000035) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1285
R&D Systems VersaClone cDNA Plasmids
1 Image
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Human Androgen R/NR3C4 (NP_000035) VersaClone cDNA Summary

Human Androgen Receptor (AR; NR3C4) is a 110 kDa member of the NR3 subfamily of the nuclear hormone receptor family. Androgen receptors are expressed by androgen-sensitive tissue (bone, prostate, testis) and exist as both ahomodimers and a heterodime in a complex with the glucocorticoid receptor. Multiple forms of the androgen receptor are known to exist. The 110 kDa 'B' form is 919 amino acids in length. Phosphorylation increases its molecular weight to 112 kDa and 114 kDa. A five amino acid deletion (amino acids 74 - 78) in AR-B has been reported. In addition, a short 'A' form of 87 kDa and 732 amino acids is also known. Expanded polyglutamine repeats in the androgen receptor are known to cause Kennedy's disease, an X-linked form of motor neuron disease.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: Androgen R/NR3C4

Long Name
Androgen Receptor
Entrez Gene IDs
367 (Human)
Alternate Names
AIS; Androgen R; androgen receptor; AndrogenR; AR; DHTR; DHTRTFM; Dihydrotestosterone receptorHYSP1; HUMARA; NR3C4; NR3C4KD; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; SMAX1SBMA; spinal and bulbar muscular atrophy

FAQs

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Tocris Small Molecules

BMS 564929

Cl-4AS-1

Flutamide

TFM-4AS-1

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