Human Calcitonin R Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Calcitonin R

Calcitonin receptor (CALCR) is a glycosylated 70 kDa seven-transmembrane G protein-coupled receptor that mediates the hypocalcemic effects of the peptide hormone, calcitonin. CALCR activation inhibits osteoclast-mediated bone resorption and enhances renal calcium excretion. CALCR polymorphisms and mutations have been associated with several bone disorders. Alternative splicing results in the deletion of 16 aa in the first cytoplasmic loop or 23 aa in the first extracellular region. Human CALCR shares 70%‑72% aa sequence identity with mouse and rat CACLR.

Product Datasheets

Related Research Areas

• Calcium-binding Proteins and Related Molecules
• Metabolic Peptide Hormones and Regulators
• Mouse Tissue-Resident Macrophage Markers
• Neural Stem Cell Markers
• Osteoblast and Osteoclast Markers
• Vasoactive Peptide Hormones and Regulators