CCR7 is a 7TM G protein-coupled receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response.
Human CCR7 (NP_001829) VersaClone cDNA
R&D Systems | Catalog # RDC0014
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Background: CCR7
Alternate Names
BLR2, CC-CKR-7, CCR7, CD197, CDw197, CMKBR7, EBI1
Gene Symbol
CCR7
UniProt
Additional CCR7 Products
Product Documents for Human CCR7 (NP_001829) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human CCR7 (NP_001829) VersaClone cDNA
For research use only
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