Human CD164 Alexa Fluor® 700-conjugated Antibody Summary
Accession # Q04900
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of CD164 in CXCL12-treated PC-3 Human Cell Line by Flow Cytometry. PC-3 prostate cancer cell line treated with Recombinant Human CXCL12 (200ng/ml, Catalog # 6448-SD) for 2 hours (filled histogram), or PC-3 cell line untreated (open histogram) was stained with Mouse Anti-Human CD164 Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB5790N). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
CD164, also known as endolyn, MGC-24, and MUC-24, is an 80‑100 kDa transmembrane sialomucin protein that is expressed by epithelial cells, T and B cells, monocytes, hematopoietic progenitor cells, and activated basophils. CD164 functions as an adhesion molecule and a negative regulator of cell proliferation. A soluble isoform is generated by alternate splicing. CD164 was identified as a potential regulator of homing in a prostate cancer screening for CXCL12-responsive adhesion molecules (1). Within the ECD, human CD164 shares approximately 53% sequence identity with mouse and rat CD164.
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