CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5).
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Immunogen
Met1-Ile300
Accession # P28907
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human CD38 PerCP‑conjugated Antibody
Detection of CD38 in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD38 PerCP-conjugated Monoclonal Antibody (Catalog # FAB2404C, filled histogram) or isotype control antibody (Catalog # IC003C, open histogram). View our protocol for Staining Membrane-associated Proteins.Detection of CD38 in Human PBMCs gated on CD19+CD3-cells by Flow Cytometry.
Human peripheral blood mononuclear cells (PBMCs) gated on CD19+CD3-cells were stained with Mouse Anti-Human CD38 PerCP-conjugated Monoclonal Antibody (Catalog # FAB2404C) and Mouse Anti-Human MS4A1/CD20 APC-conjugated Monoclonal Antibody (Catalog # FAB4225A). View our protocol for Staining Membrane-associated Proteins.Detection of CD38 in Daudi cells by Flow Cytometry
Daudi cells were stained with Mouse Anti-Human CD38 PerCP‑conjugated Monoclonal Antibody (Catalog # FAB2404C, filled histogram) or isotype control antibody (Catalog # IC003C, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human CD38 PerCP‑conjugated Antibody
Flow Cytometry
Sample: Human peripheral blood lymphocytes, human peripheral blood mononuclear cells (PBMCs) and Daudi cell line
Reviewed Applications
Read 1 review rated 5 using FAB2404C in the following applications:
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Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD38
References
- Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249.
- Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811.
- Sun, L. et al. (1999) J. Cell Biol. 146:1161.
- Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209.
- Kato, I. et al. (1995) J. Biol. Chem. 270:30045.
Long Name
Alternate Names
Gene Symbol
UniProt
Additional CD38 Products
Product Documents for Human CD38 PerCP‑conjugated Antibody
Certificate of Analysis
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Product Specific Notices for Human CD38 PerCP‑conjugated Antibody
For research use only
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Application: Flow CytometrySample Tested: Peripheral blood leukocytesSpecies: HumanVerified Customer | Posted 02/21/2018
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