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Human Cdk6 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB11636V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11636V-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Cdk6 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects recombinant human CDK-6 protein in Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1092920
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human CDK-6
Met1-Ala326
Accession # Q00534
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Cdk6

Cell division protein kinase 6 (CDK6) is an enzyme that is regulated by Cyclin D proteins and Cyclin-dependent kinase inhibitor proteins. CDK6 plays an important role in hematopoiesis and loss of CDK6 causes mild anemia, thymic atrophy and delayed G1 progression in lymphocytes.  Overexpression of CDK6 has been reported in T-cell lymphoblastic lymphoma and leukemia and in all B-lymphoid malignancies.

Long Name
Cyclin-dependent kinase 6
Entrez Gene IDs
1021 (Human); 12571 (Mouse)
Alternate Names
Cdk6; CDKN6; Cell division protein kinase 6; cyclin-dependent kinase 6; EC 2.7.11; EC 2.7.11.22; PLSTIREMGC59692; Serine/threonine-protein kinase PLSTIRE

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