Home / CL-P1/COLEC12 / Human CL-P1/COLEC12 MAb (Clone 388306)

Human CL-P1/COLEC12 MAb (Clone 388306)

Catalog #: MAB2690 Datasheet / COA / SDS

Discontinued Product

MAB2690 has been discontinued.
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Human CL-P1/COLEC12 MAb (Clone 388306) Summary

Species Reactivity
Human
Specificity
Detects human CL‑P1/COLEC12 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse CL-P1 is observed.
Source
Monoclonal Rat IgG1 Clone # 388306
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CL‑P1/COLEC12 isoform 1
Leu57-Leu742
Accession # NP_569057
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human CL-P1/COLEC12 (Catalog # 2690-CL)
under non-reducing conditions only
Flow Cytometry
2.5 µg/106 cells
HUVEC human umbilical vein endothelial cells
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CL-P1/COLEC12

Collectins are a family of Ca++-dependent, C-type lectins that contain a collagenous domain and function as recognition molecules for molecular patterns found on pathogens. Human collectin placenta 1 [CL-P1; also known as collectin sub-family member 12 and SRCL type I (scavenger receptor with C-type lectin type I)] is a 110 kDa member of the collectin family of glycoproteins. With two exceptions, all collectins are secreted. CL-P1 is the only collectin known to be membrane bound, while CL-L1 (collectin liver-1) is the only known cytoplasmic collectin.

Long Name
Collectin Placenta 1
Entrez Gene IDs
81035 (Human); 140792 (Mouse); 361289 (Rat)
Alternate Names
CL-P1; CLP1hCL-P1; COLEC12; collectin placenta 1; Collectin placenta protein 1; collectin sub-family member 12; collectin-12; NSR2; Nurse cell scavenger receptor 2; SCARA4; SCARA4NSR2; Scavenger receptor class A member 4; scavenger receptor class A, member 4; SRCL Type I; SRCLScavenger receptor with C-type lectin

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