Human Complement Component C1qA Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB4035R-100UG

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Human Complement Component C1qA Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects recombinant human Complement Component C1qA in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Complement Component C1qB is observed.
Source
Monoclonal Rat IgG2b Clone # 394107
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Complement Component C1qA
Lys110-Ala245
Accession # P02745
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Complement Component C1qA

C1qA, one of three subunits of complement component C1q, contains a collagen-like domain and a globular C1q domain. Within the globular domain, human C1qA shares 73% and 77% aa sequence identity with mouse and rat C1qA, respectively. Six disulfide-linked heterodimers of C1qA and C1qB associate with three disulfide-linked homodimers of C1qC to form C1q. Deficiency in C1qA is associated with the development of autoimmunity.

Long Name
Complement Component 1q Subcomponent, A Chain
Entrez Gene IDs
712 (Human); 12259 (Mouse); 298566 (Rat)
Alternate Names
C1QA complement component 1, q subcomponent, A chain; C1QA; Complement Component C1qA

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