Human COUP-TF II/NR2F2 Antibody

Catalog # Availability Size / Price Qty
PP-H7147-00
Detection of Human COUP-TF II/NR2F2 by Knockdown Validated
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Product Details
Citations (44)
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Human COUP-TF II/NR2F2 Antibody Summary

Species Reactivity
Human
Specificity
This antibody specifically recognizes human COUP-TF II and cross-reacts with rat COUP-TF II. This antibody does not cross-react with human COUP-TF I or EAR2. Not yet tested in other species.
Source
Monoclonal Mouse IgG2A Clone # H7147
Purification
Protein A or G purified from ascites
Immunogen
Recombinant human COUP-TF II/NR2F2
Amino Acids 43-64
Formulation
A liquid formulation in physiologic saline with 0.1% NaN3.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
This antibody can be used at 1 μg/mL with the appropriate secondary reagents to detect human COUP-TF II.
 
Immunohistochemistry
This antibody can be used at 10 ug/mL with the appropriate secondary reagents to detect human COUP-TF II alpha.
 
Immunoprecipitation
Optimal dilutions should be determined by each laboratory.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Knockdown Validated Detection of Human COUP-TF II/NR2F2 by Knockdown Validated View Larger

Detection of Human COUP-TF II/NR2F2 by Knockdown Validated Reduction of COUP-TFII or nucleolin decreases RAR beta 2 transcription in MCF-7 cells.MCF-7 (A) and T47D (B) cells were transfected with control siRNA or an siRNA targeting nucleolin for 48 h. T47D cells were treated with EtOH or 1 µM atRA for 24 h. Q-PCR for nucleolin (NCL) and RARB2. Values are the average of triplicates. C, Western blot showing COUP-TFII and RAR beta 2 expression after transfection with siCOUP-TFII. Values are relative to beta -actin. MCF-7 were transfected with siControl or siCOUP-TFII for 48 h and treated with 1 µM atRA for 6 h. Q-PCR was also performed for RRIG1. P<0.001 * versus control or ** versus atRA. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0038278), licensed under a CC-BY license. Not internally tested by R&D Systems.

Knockdown Validated Detection of Human COUP-TF II/NR2F2 by Knockdown Validated View Larger

Detection of Human COUP-TF II/NR2F2 by Knockdown Validated Loss of miR-101 promotes cancer metastasis through de-repression of COUP-TFII expression.(a) LNCaP and PC3 cells were individually treated with 50 nM of miR-101 and miR-27a mimic for 48 h and then invasion assays were performed for an additional 16 h (n=3). *P<0.05 (two-sided Student's t-test) compared with the control group. (b) Representative western blot showed the levels of COUP-TFII, E-cadherin, vimentin and beta -actin in PC3 cells stably knocked down by COUP-TFII. (c) LNCaP and PC3 cells stably knocked-down of COUP-TFII were used to perform cell invasion assay. Invaded cells were stained and counted (lower panel) (n=3). Representative western blot showed the knockdown efficiency of COUP-TFII (upper panel). *: P<0.05 (two-sided Student's t-test) compared with control group. (d) PC3 cells carrying an inducible miR-101 in the absence and presence of doxycycline, and re-expression of COUP-TFII were used to perform invasion assays (n=3). Representative western blot showed the levels of COUP-TFII and beta -actin (left). Invaded cells were counted and results are shown in the right panel. *: P<0.05 (two-sided Student's t-test) (e) 22RV-1 cells were treated with miR-101 inhibitor (antisense RNA) in conjunction with knockdown of COUP-TFII and used for invasion assays (n=3). Representative western blot show the levels of COUP-TFII and beta -actin (left). Invaded cells were counted and result is shown in the right panel. *: P<0.05 (two-sided Student's t-test). (f) LNCaP cells containing a construct with inducible expression of COUP-TFII shRNA and constructs expressing with anti-miR-101 and anti-mir-27a were orthotopically injected into NOD-SCID mouse prostate. In addition these cells also contain a luciferase reporter to detect cancer cells. After the tumour size was bigger than 50 mm3, drinking water with or without doxycycline (1 mg ml−1) was given to the mice for 6 weeks to induce the COUP-TFII shRNA to repress COUP-TFII expression. Representative bioluminescence results show the status of tumour growth in different groups. (g) Quantification result of luminance from IVIS (control: n=5; anti-miR-101/27a(−): n=6; anti-miR-101/27a(+): n=7. *: P<0.05 (two-sided Student's t-test). (h) Immunohistochemical stain showed the metastatic tumour cells located in the mouse lymph node are positive for AR. Scale bar: 100 μM (low power); and 200 μM (high power). SCID, severe combined immunodeficient. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/ncomms11418), licensed under a CC-BY license. Not internally tested by R&D Systems.

Knockdown Validated Detection of Human COUP-TF II/NR2F2 by Knockdown Validated View Larger

Detection of Human COUP-TF II/NR2F2 by Knockdown Validated Loss of miR-101 promotes cancer metastasis through de-repression of COUP-TFII expression.(a) LNCaP and PC3 cells were individually treated with 50 nM of miR-101 and miR-27a mimic for 48 h and then invasion assays were performed for an additional 16 h (n=3). *P<0.05 (two-sided Student's t-test) compared with the control group. (b) Representative western blot showed the levels of COUP-TFII, E-cadherin, vimentin and beta -actin in PC3 cells stably knocked down by COUP-TFII. (c) LNCaP and PC3 cells stably knocked-down of COUP-TFII were used to perform cell invasion assay. Invaded cells were stained and counted (lower panel) (n=3). Representative western blot showed the knockdown efficiency of COUP-TFII (upper panel). *: P<0.05 (two-sided Student's t-test) compared with control group. (d) PC3 cells carrying an inducible miR-101 in the absence and presence of doxycycline, and re-expression of COUP-TFII were used to perform invasion assays (n=3). Representative western blot showed the levels of COUP-TFII and beta -actin (left). Invaded cells were counted and results are shown in the right panel. *: P<0.05 (two-sided Student's t-test) (e) 22RV-1 cells were treated with miR-101 inhibitor (antisense RNA) in conjunction with knockdown of COUP-TFII and used for invasion assays (n=3). Representative western blot show the levels of COUP-TFII and beta -actin (left). Invaded cells were counted and result is shown in the right panel. *: P<0.05 (two-sided Student's t-test). (f) LNCaP cells containing a construct with inducible expression of COUP-TFII shRNA and constructs expressing with anti-miR-101 and anti-mir-27a were orthotopically injected into NOD-SCID mouse prostate. In addition these cells also contain a luciferase reporter to detect cancer cells. After the tumour size was bigger than 50 mm3, drinking water with or without doxycycline (1 mg ml−1) was given to the mice for 6 weeks to induce the COUP-TFII shRNA to repress COUP-TFII expression. Representative bioluminescence results show the status of tumour growth in different groups. (g) Quantification result of luminance from IVIS (control: n=5; anti-miR-101/27a(−): n=6; anti-miR-101/27a(+): n=7. *: P<0.05 (two-sided Student's t-test). (h) Immunohistochemical stain showed the metastatic tumour cells located in the mouse lymph node are positive for AR. Scale bar: 100 μM (low power); and 200 μM (high power). SCID, severe combined immunodeficient. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/ncomms11418), licensed under a CC-BY license. Not internally tested by R&D Systems.

Knockdown Validated Detection of Human COUP-TF II/NR2F2 by Knockdown Validated View Larger

Detection of Human COUP-TF II/NR2F2 by Knockdown Validated FOXM1 and CENPF are downstream targets of COUP-TFII in PCa.(a) Gene expression profile of COUP-TFII knockdown PC3 cells (GSE33182) was downloaded from GEO database and analysed using GenePattern. Genes with P<0.05, FOLD CHANGE >1.5-fold are represented as a heatmap. The gene symbol of FOXM1 and CENPF genes after knockdown of COUP-TFII are annotated in red colour. The others were FOXM1 and CENPF co-regulated genes annotated in black colour. siCtrl: knockdown scramble control; siCII: knockdown of COUP-TFII. (b) A representative western blot shows the level of COUP-TFII in PC3 cells transfected with two different siRNAs against COUP-TFII for 72 h (upper panel). Levels of FOXM1 and CENPF are quantified by RT-qPCR (lower panel) (n=3). *P<0.05 (two-sided Student's t-test) compared with the control group (siCON). (c) A cartoon shows the FOXM1 and CENPF loci. COUP-TFII-binding sites are annotated by a black rectangle (upper panel). ChIP results are shown in the PC3 cells treated with control and two different siRNAs against COUP-TFII for 72 h (lower panel) (n=3). *P<0.05 (two-sided Student's t-test) compared with control. (d) FOXM1 and CENPF promoter activities were measured in PC3 cells carrying an inducible COUP-TFII gene in the absence or the presence of doxycycline for 48 h (n=3). *P<0.05 (two-sided Student's t-test). (e) FOXM1 and CENPF promoter activities were measured in control or stably knocked-down COUP-TFII in PC3 cells for 48 h (n=3). *P<0.05 (two-sided Student's t-test). (f) PC3 cells carrying with inducible COUP-TFII-Flag gene were treated with or without doxycycline for 48 h and then transfected with individual siRNA against FOXM1 and CENPF or double knockdown of FOXM1 and CENPF for an additional 48 h. western blot (left panel) shows the level of COUP-TFII, CENPF and FOXM1 expression. Invasion assay (right panel) was performed by using those cells (n=3). *P<0.05 (two-sided Student's t-test) compared with control. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/ncomms11418), licensed under a CC-BY license. Not internally tested by R&D Systems.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
This antibody is stable for greater than six months when held at -20° C in a manual defrost freezer or at -70° C. Upon thawing, the antibody can be stored at 2° - 8° C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: COUP-TF II/NR2F2

Chicken ovalbumin upstream promoter transcription factor II (COUP-TF II, ARP-1, COUP-TFB; NR2F2) is a member of the orphan nuclear receptorfamily. COUP-TF II is expressed in the tongue, follicles of vibrissae, cochIea and in stroma of the nasal septum. COUP-TF II has roles in angiogenesis, vascular remodeling and heart development. COUP-TFs were shown to interact with a number of other nuclear receptors.

Long Name
COUP Transcription Factor 1/Nuclear Receptor Subfamily 2, Group F, Member 2
Entrez Gene IDs
7026 (Human)
Alternate Names
Apolipoprotein A-I regulatory protein 1; ARP-1; ARP1ADP-ribosylation factor related protein 1; chicken ovalbumin upstream promoter transcription factor 2; COUP transcription factor 2; COUP transcription factor II; COUPTF II; COUP-TF II; COUP-TF2; COUPTFB; COUPTFII; COUP-TFII; MGC117452; NR2F2; Nuclear receptor subfamily 2 group F member 2; nuclear receptor subfamily 2, group F, member 2; SVP40; TFCOUP2apolipoprotein AI regulatory protein 1

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Citations for Human COUP-TF II/NR2F2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

44 Citations: Showing 1 - 10
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  1. Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons
    Authors: ES Liau, S Jin, YC Chen, WS Liu, M Calon, S Nedelec, Q Nie, JA Chen
    Oncogene, 2023-01-03;14(1):46.
  2. Molecular and electrophysiological evaluation of human cardiomyocyte subtypes to facilitate generation of composite cardiac models
    Authors: J Li, A Wiesinger, L Fokkert, BJ Boukens, AO Verkerk, VM Christoffe, GJJ Boink, HD Devalla
    Journal of tissue engineering, 2022-10-18;13(0):2041731422112.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  3. Modeling human multi-lineage heart field development with pluripotent stem cells
    Authors: D Yang, J Gomez-Garc, S Funakoshi, T Tran, I Fernandes, GD Bader, MA Laflamme, GM Keller
    Cell Stem Cell, 2022-09-01;29(9):1382-1401.e8.
    Species: Human
    Sample Types: Organoid
    Applications: ICC
  4. The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC
    Authors: Feng Liu, Dandan Long, Wenjun Huang, Wanling Peng, Huan Lan, Yafei Zhou et al.
    International Journal of Stem Cells
  5. Somatic cell fate maintenance in mouse fetal testes via autocrine/paracrine action of AMH and activin B
    Authors: KF Rodriguez, PR Brown, CM Amato, B Nicol, CF Liu, X Xu, HH Yao
    Nature Communications, 2022-07-15;13(1):4130.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  6. Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency
    Authors: Wei Feng, Hannah Schriever, Shan Jiang, Abha Bais, Haodi Wu, Dennis Kostka et al.
    Communications Biology
  7. BRN2 as a key gene drives the early primate telencephalon development
    Authors: X Zhu, Y Guo, C Chu, D Liu, K Duan, Y Yin, C Si, Y Kang, J Yao, X Du, J Li, S Zhao, Z Ai, Q Zhu, W Ji, Y Niu, T Li
    Science Advances, 2022-03-04;8(9):eabl7263.
    Species: Primate (Macaca fascicularis)
    Sample Types: Whole Tissue
    Applications: IHC
  8. Anti-recombination function of MutS alpha restricts telomere extension by ALT-associated homology-directed repair
    Authors: Barroso-GonzAlez J, GarcIa-ExpOsito L, Galaviz P et al.
    Cell reports
  9. The embryonic ontogeny of the gonadal somatic cells in mice and monkeys
    Authors: K Sasaki, A Oguchi, K Cheng, Y Murakawa, I Okamoto, H Ohta, Y Yabuta, C Iwatani, H Tsuchiya, T Yamamoto, Y Seita, M Saitou
    Cell Reports, 2021-05-04;35(5):109075.
    Species: Cynomolgus Monkey
    Sample Types: Whole Tissue
    Applications: IHC
  10. Molecular Actions Underlying Wolffian Duct Regression in Sexual Differentiation of Murine Reproductive Tracts
    Authors: Fei Zhao, Sara A. Grimm, Humphrey Hung-Chang Yao
    Sexual Development
  11. Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2
    Authors: Gan Zhao, Aaron I. Weiner, Katherine M. Neupauer, Maria Fernanda de Mello Costa, Gargi Palashikar, Stephanie Adams-Tzivelekidis et al.
    Science Advances
  12. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
    Authors: L Wang, CM Cheng, J Qin, M Xu, CY Kao, J Shi, E You, W Gong, LP Rosa, P Chase, L Scampavia, F Madoux, T Spicer, P Hodder, HE Xu, SY Tsai, MJ Tsai
    Sci Adv, 2020-04-29;6(18):eaaz8031.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  13. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
    Authors: L Wang, CM Cheng, J Qin, M Xu, CY Kao, J Shi, E You, W Gong, LP Rosa, P Chase, L Scampavia, F Madoux, T Spicer, P Hodder, HE Xu, SY Tsai, MJ Tsai
    Sci Adv, 2020;6(18):eaaz8031.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  14. The Nuclear Receptor COUP-TFII Regulates Amhr2 Gene Transcription via a GC-Rich Promoter Element in Mouse Leydig Cells
    Authors: Samir Mehanovic, Raifish E Mendoza-Villarroel, Robert S Viger, Jacques J Tremblay
    Journal of the Endocrine Society
  15. Immature excitatory neurons develop during adolescence in the human amygdala
    Authors: SF Sorrells, MF Paredes, D Velmeshev, V Herranz-Pé, K Sandoval, S Mayer, EF Chang, R Insausti, AR Kriegstein, JL Rubenstein, J Manuel Gar, EJ Huang, A Alvarez-Bu
    Nat Commun, 2019-06-21;10(1):2748.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  16. Retinoic Acid Regulates Endothelial ?-catenin Expression and Pericyte Numbers in the Developing Brain Vasculature
    Authors: S Bonney, BJC Dennison, M Wendlandt, JA Siegenthal
    Front Cell Neurosci, 2018-12-05;12(0):476.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  17. Magnetic Resonance Imaging and Histopathological Visualization of Human Dural Lymphatic Vessels
    Authors: Seung-Kwon Ha, Govind Nair, Martina Absinta, Nicholas J. Luciano, Daniel S. Reich
    BIO-PROTOCOL
  18. Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI
    Authors: M Absinta, SK Ha, G Nair, P Sati, NJ Luciano, M Palisoc, A Louveau, KA Zaghloul, S Pittaluga, J Kipnis, DS Reich
    Elife, 2017-10-03;6(0):.
    Species: Human, Primate
    Sample Types: Whole Tissue
    Applications: IHC-P
  19. Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow
    Authors: JJ Hwa, N Beckouche, L Huang, Y Kram, H Lindskog, RA Wang
    Sci Rep, 2017-09-20;7(1):11965.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  20. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017-08-03;21(2):179-194.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  21. The transcription factor Foxg1 promotes optic fissure closure in the mouse by suppressing Wnt8b in the nasal optic stalk
    Authors: R Smith, YT Huang, T Tian, D Vojtasova, O Mesalles-N, SM Pollard, T Pratt, DJ Price, V Fotaki
    J. Neurosci., 2017-07-20;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  22. Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2
    Authors: Kim Brint Pedersen, Harshita Chodavarapu, Eric Lazartigues
    Journal of the Endocrine Society
  23. Single-Cell Profiling of an In�Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation
    Authors: JL Close, Z Yao, BP Levi, JA Miller, TE Bakken, V Menon, JT Ting, A Wall, AR Krostag, ER Thomsen, AM Nelson, JK Mich, RD Hodge, SI Shehata, IA Glass, S Bort, NV Shapovalov, NK Ngo, JS Grimley, JW Phillips, CL Thompson, S Ramanathan, E Lein
    Neuron, 2017-03-08;93(5):1035-1048.e5.
  24. Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII
    Authors: Man Chu, Taotao Li, Bin Shen, Xudong Cao, Haoyu Zhong, Luqing Zhang et al.
    eLife
  25. Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2 and COUP-TFII in early fetal human telencephalon
    Authors: Ayman Alzu'bi
    Brain Struct Funct, 2016-11-30;0(0):.
    Species: Human
    Sample Types: Whole Tissue
  26. COUP-TFII regulates satellite cell function and muscular dystrophy
    J Clin Invest, 2016-09-12;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Whole Tissue
    Applications: ChIP, IHC
  27. Diverse Functions of Retinoic Acid in Brain Vascular Development
    J Neurosci, 2016-07-20;36(29):7786-801.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  28. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer
    Authors: SC Lin, CY Kao, HJ Lee, CJ Creighton, MM Ittmann, SJ Tsai, SY Tsai, MJ Tsai
    Nat Commun, 2016-04-25;7(0):11418.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  29. Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.
    Authors: Tanwar V, Bylund J, Hu J, Yan J, Walthall J, Mukherjee A, Heaton W, Wang W, Potet F, Rai M, Kupershmidt S, Knapik E, Hatzopoulos A
    Stem Cells, 2014-07-01;32(7):1774-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  30. 5-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines
    Authors: Numan Al-Rayyan, Lacey M. Litchfield, Margarita M. Ivanova, Brandie N. Radde, Alan Cheng, Ahmed Elbedewy et al.
    Cancer Letters
  31. Molecular identification of venous progenitors in the dorsal aorta reveals an aortic origin for the cardinal vein in mammals.
    Authors: Lindskog, Henrik, Kim, Yung Hae, Jelin, Eric B, Kong, Yupeng, Guevara-Gallardo, Salvador, Kim, Tyson N, Wang, Rong A
    Development, 2014-03-01;141(5):1120-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  32. Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes.
    Authors: Boyer-Di Ponio J, El-Ayoubi F, Glacial F, Ganeshamoorthy K, Driancourt C, Godet M, Perriere N, Guillevic O, Couraud P, Uzan G
    PLoS ONE, 2014-01-02;9(1):e84179.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  33. Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice
    Authors: Jean-François Schmouth, Mauro Castellarin, Stéphanie Laprise, Kathleen G Banks, Russell J Bonaguro, Simone C McInerny et al.
    BMC Biology
  34. COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells.
    Authors: Litchfield L, Appana S, Datta S, Klinge C
    Mol Cell Endocrinol, 2013-10-17;382(1):358-67.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation, Western Blot
  35. Atrial Identity Is Determined by a COUP-TFII Regulatory Network
    Authors: San-pin Wu, Chiang-Min Cheng, Rainer B. Lanz, Tiannan Wang, Jonathan L. Respress, Sameer Ather et al.
    Developmental Cell
  36. BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development
    Authors: Reema B. Davis, Carol D. Curtis, Courtney T. Griffin
    Development
  37. Endogenous Purification Reveals GREB1 as a Key Estrogen Receptor Regulatory Factor.
    Authors: Mohammed H
    Oncogene, 2013-02-09;3(2):342-9.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  38. Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
    Authors: Litchfield LM, Riggs KA, Hockenberry AM, Oliver LD, Barnhart KG, Cai J, Pierce WM, Ivanova MM, Bates PJ, Appana SN, Datta S, Kulesza P, McBryan J, Young LS, Klinge CM
    PLoS ONE, 2012-05-31;7(5):e38278.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  39. Chicken Ovalbumin Upstream Promoter Transcription Factor II Regulates Renin Gene Expression.
    Authors: Mayer S, Roeser M, Lachmann P
    J. Biol. Chem., 2012-05-29;287(29):24483-91.
    Species: Human, Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  40. Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents.
    Authors: van den Driesche S, Walker M, McKinnell C, Scott HM, Eddie SL, Mitchell RT, Seckl JR, Drake AJ, Smith LB, Anderson RA, Sharpe RM
    PLoS ONE, 2012-05-17;7(5):e37064.
    Species: Human, Rat
    Sample Types: Whole Tissue
    Applications: IHC
  41. A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiation.
    Authors: Rosa A, Brivanlou AH
    EMBO J., 2010-12-10;30(2):237-48.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  42. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
    Authors: Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY
    J. Clin. Invest., 2010-04-01;120(5):1694-707.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Whole Tissue
    Applications: IHC-P, Western Blot
  43. SCF induces gamma-globin gene expression by regulating downstream transcription factor COUP-TFII.
    Authors: Aerbajinai W, Zhu J, Kumkhaek C, Chin K, Rodgers GP
    Blood, 2009-04-28;114(1):187-94.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  44. The transcription factor COUP-TFII is negatively regulated by insulin and glucose via Foxo1- and ChREBP-controlled pathways.
    Authors: Perilhou A, Tourrel-Cuzin C, Kharroubi I, Henique C, Fauveau V, Kitamura T, Magnan C, Postic C, Prip-Buus C, Vasseur-Cognet M
    Mol. Cell. Biol., 2008-09-02;28(21):6568-79.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot

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Human COUP-TF II/NR2F2 Antibody
By Anonymous on 08/17/2021
Application: IHC Sample Tested: Kidney angiomyolipoma Species: Human