Human CRLR Alexa Fluor® 647-conjugated Antibody Summary
Accession # Q16602
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: CRLR
The calcitonin receptor-like receptor (CRLR), a class B GPCR, forms a heterodimer with receptor activity-modifying protein 2 (RAMP2), and serves as the adrenomedullin (AM) receptor to control neovascularization, while CRLR and RAMP1 form the calcitonin gene-related peptide (CGRP) receptor. CALCRL is pharmacologically identical to CGRP receptor-1, a putative molecular target of CGRP and adrenomedullin. CALCRL is predominantly expressed in the lung and heart.
Product Datasheets
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