Human Cystatin SN Antibody [Biotin]

R&D Systems | Catalog # BAF1285

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Cystatin SN Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Cystatin SN
Trp21-Ser141
Accession # P01037

Specificity

Detects human Cystatin SN in Western blots. In Western blots, approximately 30% cross-reactivity with recombinant human (rh) Cystatin SA is observed, 15% cross-reactivity with rhCystatin S is observed, 5% cross‑reactivity with rhCystatin D is observed, and less than 1% cross‑reactivity with rhCystatin A, rhCystatin B, rhCystatin C, rhCystatin E/M, and rhCystatin F is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Cystatin SN Antibody [Biotin]

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Cystatin SN (Catalog # 1285-PI)

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Cystatin SN

Cystatin SN is a member of family 2 of the cystatin superfamily (1). Together with cystatins S and SA, it is produced by the salivary gland and secreted largely in the submandibular/sublingual saliva (2). Cystatin SN inhibits members of the papain family including cathepsins B, C, H and L (3).

References

  1. Abrahamson, M. (1994) Methods Enzymol. 244:685.
  2. Baron, A.C. et al. (1999) Oral Dis. 5:344.
  3. Baron, A. et al. (1999) Oral Dis. 5:234.

Alternate Names

CST1

Entrez Gene IDs

1469 (Human)

Gene Symbol

CST1

UniProt

P01037

Additional Cystatin SN Products

Product Documents for Human Cystatin SN Antibody [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Cystatin SN Antibody [Biotin]

For research use only

Related Research Areas

Cysteine Proteases and Regulators

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