Human EphA10 Alexa Fluor® 488-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB5188G-100UG

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Human EphA10 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human EphA10 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human EphA1, A2, A5, A6, B2, B3, B4, B6, recombinant mouse EphA3, A4, or A8 is observed.
Source
Monoclonal Mouse IgG2b Clone # 494130
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human EphA10
Glu34-Glu283 (predicted)
Accession # Q5JZY3
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: EphA10

EphA10 is a member of the Eph family of receptor tyrosine kinases that are activated by binding members of the Ephrin ligand family. EphA10 preferentially binds Ephrin-A3, -A4 and -A5.  EphA10 mRNA expression appears limited to the testis, unlike most Ephs that are expressed in developing and adult neural tissue. Human EphA10 extracellular domain (ECD) shares 95% and 88% amino acid identity with mouse and rat EphA10, respectively. Of three alternately spliced isoforms, one is truncated within the ECD and another within the cytoplasmic domain.

Long Name
Eph Receptor A10
Entrez Gene IDs
284656 (Human); 298528 (Rat)
Alternate Names
EC 2.7.10.1; EPH receptor A10; EphA10; EphA10s protein; ephrin type-A receptor 10; FLJ16103; FLJ33655; MGC43817

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