Human FGFR3 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB7661U Datasheet / COA / SDS

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FAB7661U-100UG

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Human FGFR3 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects the IIIb and IIIc isoforms of human FGF R3. It does not cross-react with mouse FGF R3 or with any isoforms of recombinant human (rh) FGF R1 or rhFGF R2.

Source

Monoclonal Mouse IgG1 Clone # 136318

Purification

Protein A or G purified

Immunogen

Pool of NS0-derived recombinant human FGFÂ R3 alpha (IIIb) and Sf21-derived FGF R3 alphaÂ (IIIc)

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Neutralization

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FGFR3

The extracellular domain of FGF R3 includes 3 Ig-like domains. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms.

Long Name

Fibroblast Growth Factor Receptor 3

Entrez Gene IDs

2261 (Human); 14184 (Mouse)

Alternate Names

CD333; CEK; EC 2.7.10; FGF R3; FGFR3; fibroblast growth factor receptor 3; HSFGFR3EX; JTK4; JTK4thanatophoric dwarfism