Human Flap Endonuclease (FEN-1)/Buffer
Human Flap Endonuclease (FEN-1)/Buffer Summary
Specifications
Product Datasheets
Background: FEN-1
The FEN-1 enzyme is active in base excision repair (BER) pathways. Once the DNA glycosylase removes the desired nucleotide stretch, a DNA polymerase synthesizes the complementary nucleotides for replacement. To complete the DNA repair, the FEN-1 enzyme removes the extra flap of nucleotides and DNA ligase finishes the repair.
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