Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG
View all FoxM1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human FoxM1
Thr642-Gln763
Accession # Q08050

Specificity

Detects human FoxM1 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) FoxJ1 is observed and less than 1% cross-reactivity with rhFoxB2, rhFoxC2, rhFoxD3, rhFoxF1, rhFoxH1, rhFoxO3A, rhFoxP1, and rhFoxP3 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human FoxM1 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human FoxM1

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FoxM1

FoxM1 (Forkhead box protein M1; also FKHL16, HFH11 and WIN) is a 90‑100 kDa member of the winged helix transcription factor gene family. It is expressed in proliferating and tumor cells and promotes the transition from G1 to S phase and G2 to M phase within the cell cycle. Human FoxM1 is 763 amino acids (aa) in length. It contains three PEST sequences (aa 22‑34, 460‑472 and 478‑515), a forkhead DNA binding domain (aa 235‑327), a Pro/Ser/Thr-rich region (aa 480‑513) and a phosphorylation site at Ser704. There are at least two splice variants. The first shows a 38 aa insertion after Val423. This blocks FoxM1 transcriptional activation activity. The second variant shows a deletion of aa 326‑340. Over aa 642‑763, human FoxM1 shares 73% aa identity with mouse FoxM1.

Long Name

Forkhead Box M1

Alternate Names

FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP-2, PIG29, Trident

Entrez Gene IDs

2305 (Human); 14235 (Mouse); 58921 (Rat)

Gene Symbol

FOXM1

UniProt

Q08050

Additional FoxM1 Products

Product Documents for Human FoxM1 Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human FoxM1 Biotinylated Antibody

For research use only

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