Human GluR6/GRIK2 (NP_068775) VersaClone cDNA

Name: Human GluR6/GRIK2 (NP_068775) VersaClone cDNA
Brand: R&D Systems
SKU: RDC0968
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC0968

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_068775

Background: GluR6/GRIK2

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem, whereas the four epsilon subunits display limited distribution.

Long Name

Glutamate Receptor 6

Alternate Names

EAA4, GLR6, GluK2, GLUK6, MRT6

Entrez Gene IDs

2898 (Human); 14806 (Mouse); 54257 (Rat)

Gene Symbol

GRIK2

UniProt

NP_068775

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Product Specific Notices for Human GluR6/GRIK2 (NP_068775) VersaClone cDNA

For research use only

Related Research Areas

Neurotransmitter G Protein-Coupled Receptors

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