IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs. IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals. Down-regulation of the receptor is accomplished by ubiquitination and degradation.
Human IFN‑ alpha / beta R1 Biotinylated Antibody
R&D Systems | Catalog # BAF245
Key Product Details
Species Reactivity
Human
Applications
Western Blot, Flow Cytometry
Label
Biotin
Antibody Source
Polyclonal Goat IgG
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Product Specifications
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IFN-alpha / beta R1
Lys28-Lys436
Accession # AAA52730
Lys28-Lys436
Accession # AAA52730
Specificity
Detects human IFN-alpha / beta R1 in Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human IFN‑ alpha / beta R1 Biotinylated Antibody
Application
Recommended Usage
Flow Cytometry
2.5 µg/106 cells
Sample: U937 human histiocytic lymphoma cell line
Sample: U937 human histiocytic lymphoma cell line
Western Blot
0.1 µg/mL
Sample: Recombinant Human IFN-alpha / beta R1
Sample: Recombinant Human IFN-alpha / beta R1
Flow Cytometry Panel Builder
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Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: IFN-alpha/beta R1
Long Name
Interferon alpha/beta Receptor 1
Alternate Names
IFN-aR1, IFN-bR1, IFNAR1, IFNbR1
Gene Symbol
IFNAR1
UniProt
Additional IFN-alpha/beta R1 Products
Product Documents for Human IFN‑ alpha / beta R1 Biotinylated Antibody
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human IFN‑ alpha / beta R1 Biotinylated Antibody
For research use only
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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- Western Blot Protocol
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- Western Blot Troubleshooting
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- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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Associated Pathways
