Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
Human IFN-alpha Multi-Subtype ELISA Kit
R&D Systems | Catalog # 41105-1
New Version Available:
DFNAS0
NEW
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Key Product Details
Assay Length
3.25 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 µL)
Sensitivity
12.5 pg/mL
Assay Range
12.5-500 pg/mL (Cell Culture Supernates)
156-5000 pg/mL (Cell Culture Supernates)
156-5000 pg/mL (Cell Culture Supernates)
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Product Specifications
Measurement
Quantitative ELISA
Detection Method
Colorimetric - 450nm (TMB)
Conjugate
Biotin
Species
Human
Specificity
Human IFN-alpha
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.
Background: IFN-alpha
Long Name
Interferon alpha
Alternate Names
IFNalpha, LeIF D
Entrez Gene IDs
3440 (Human)
Gene Symbol
IFNA2
Additional IFN-alpha Products
Product Documents for Human IFN-alpha Multi-Subtype ELISA Kit
Certificate of Analysis
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Product Specific Notices for Human IFN-alpha Multi-Subtype ELISA Kit
For research use only
Citations for Human IFN-alpha Multi-Subtype ELISA Kit
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