Human IFN-alpha Serum Sample ELISA Kit

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Product Details
Citations (4)
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Human IFN-alpha Serum Sample ELISA Kit Summary

Assay Length
3.25 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (100 uL), Plasma (100 uL)
12.5 pg/mL
Assay Range
12.5 - 1,000 pg/mL (Cell Culture Supernates, Serum, Plasma)
Human IFN-alpha
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
No significant interference observed with available related molecules.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name:
Interferon alpha
Entrez Gene IDs:
3440 (Human)
Alternate Names:
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

Citations for Human IFN-alpha Serum Sample ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
    Authors: S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, LL Yasukawa, X Li, CJ Kuo, DA Solomon, JE Carette, HB Greenberg
    Nat Commun, 2018-04-16;9(1):1485.
    Species: Human
    Sample Types: Cell Culture Supernates
  2. Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.
    Authors: Liu L, Cao Z, Chen J
    J. Biol. Chem., 2012-02-16;287(15):11899-910.
    Species: Human
    Sample Types: Serum
  3. Alpha interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response.
    Authors: Cheng G, Zhao X, Yan W, Wang W, Zuo X, Huang K, Liu Y, Chen J, Wang J, Cong W, Liu M, Gao H, Chen J, Lu Y, Zheng Z
    Vaccine, 2007-05-24;25(28):5199-208.
    Species: Porcine
    Sample Types: Plasma
  4. Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma.
    Authors: Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M
    J. Neuroimmunol., 2006-03-29;175(1):169-75.
    Species: Human
    Sample Types: Serum


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