Human IL-7R alpha/CD127 (NP_002176) VersaClone cDNA

R&D Systems | Catalog # RDC0962

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Key Product Details

Species

Human

Accession Number

NP_002176

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: IL-7R alpha/CD127

The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7R) comprises the IL-7R alpha chain in association with the common gamma chain (gamma c). Both IL-7R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7R alpha show 64% amino acid sequence identity. IL-7R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.

Long Name

Interleukin 7 Receptor alpha

Alternate Names

CD127, IL-7 R alpha, IL-7Ra, IL7R, IL7R alpha

Entrez Gene IDs

3575 (Human); 16197 (Mouse); 294797 (Rat); 102143679 (Cynomolgus Monkey)

Gene Symbol

IL7R

UniProt

NP_002176

Additional IL-7R alpha/CD127 Products

Product Documents for Human IL-7R alpha/CD127 (NP_002176) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human IL-7R alpha/CD127 (NP_002176) VersaClone cDNA

For research use only

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