Detection of LAIR1 in Human Lymphocytes by Flow Cytometry. Human lymphocytes were stained with Mouse Anti-Human LAIR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB2664P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
LAIR1 is an inhibitory receptor belonging to the Ig superfamily. It is
a type I transmembrane protein with one extracellular Ig-like domain
and two cytoplasmic ITIMs. Four LAIR1 splice variants exist. LAIR1b has
a 17 aa deletion outside the Ig loop in the extracellular domain. It
differs from LAIR1c by one amino acid (aa) residue. LAIR1d has a 77 aa truncation in
the cytoplasmic domain. LAIR1 is expressed on NK cells, T cells, B
cells, monocytes, dendritic cells and most thymocytes. The
extracellular domain of human LAIR1 shares 40% aa sequence identity with that of
the mouse ortholog.
R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.