Human MAO-A Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: MAO-A

MAO-A (Monoamine oxidase type A and Amine oxidase [flavin-containing] A)  is a 60 kDa (predicted) member of the flavin monoamine oxidase family of proteins.  MAO- A is an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. It localizes to the outer mitochondrial membrane. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome, a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Over aa 1-497, human MOA-A shares 88% aa sequence identity with mouse MOA-A.

Product Datasheets

Related Research Areas

• Additional Reduction/Oxidation (Redox) Enzymes
• Neurotransmitters, Neuroactive Molecules and Associated Enzymes
• Oxygenases/Hydroxylases
• Parkinson's Disease Related Molecules
• Redox Enzymes