Human MMP-15/MT2-MMP Catalytic Domain Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB916R-100UG

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Human MMP-15/MT2-MMP Catalytic Domain Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human MMP‑15/MT2‑MMP Catalytic Domain in Western blots. In Western blots, no cross-reactivity with the catalytic domain of recombinant human MMP-14 (MT1-MMP) or rhMMP-16 (MT3-MMP) is observed.
Source
Monoclonal Mouse IgG1 Clone # 130516
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human MMP-15
aa 132-625
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunoprecipitation
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MMP-15/MT2-MMP

MMP-15, also known as membrane-type 2 (MT2) MMP, is a cell surface endopeptidase that plays a role in tumor invasion and metastasis.

Long Name
Matrix Metalloproteinase 15/Membrane Type 2 MMP
Entrez Gene IDs
4324 (Human)
Alternate Names
EC 3.4.24; EC 3.4.24.-; EC 3.4.24.80; matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15 (membrane-inserted); Membrane-type matrix metalloproteinase 2; Membrane-type-2 matrix metalloproteinase; MMP15; MMP-15; MT2-MMP; MT2-MMPMT2MMP; MTMMP2MT-MMP 2; SMCP-2matrix metalloproteinase-15

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