Human/Mouse ERK5/BMK1 Alexa Fluor® 350-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: ERK5/BMK1

Extracellular signal-regulated kinase 5 (ERK5), also known as big mitogen-activated protein kinase 1 (BMK1) and MAPK7, is activated by a several mechanisms, including receptor tyrosine kinases, G protein-coupled receptors, and osmotic stress. Like ERK1 and ERK2, ERK5 contains the conserved Thr-Glu-Tyr activation motif in its activation loop. Unlike these ERKs, however, ERK5 contains a unique C-terminal domain that regulates its activation and nuclear translocation. ERK5’s upstream MAPK kinase has been identified as MEK5.

Product Datasheets

Related Research Areas

• Cancer Biomarkers
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Kinases and Phosphatases in Endothelial Cells
• Kinases and Phosphatases in VSMC
• Neurotrophin/Trk Family
• ROS and Stress Resistance
• Search Kinases and Phosphatases