FGF-23 Antibody (283511)

Detection of Mouse FGF-23 by Western Blot

Effects of conditional deletion of Fgfr1 in Hyp osteocytes on gross appearance and bone-related gene expressions in 6-week-old mice.(A) Gross appearance, tail length, and body weight. Compared with control mice, Fgfr1Dmp1-cKO-null mice had normal gross appearance and body weight. However, Hyp mice showed considerably shorter tail length and lower body weight, compound Hyp;Fgfr1Dmp1-cKO-null mice displayed intermediate tail length and body weight between control and Hyp mice. Data are mean ± S.D. from 5–6 individual mice. (B and C) Western blot analysis of total Fgf2 and Fgf23 protein levels in bone. A representative Fgf2, Fgf23, and beta -Actin gel were shown in upper, middle, and lower panels of B, respectively. The intensity of bands was quantified using Image J software (https://rsb.info.nih.gov/ij/), and the data shown in C are mean ± S.D. from three independent experiments. Values sharing the same superscript in different groups are not significantly different at P<0.05. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0104154), licensed under a CC-BY license. Not internally tested by R&D Systems.