Home / GSK-3 alpha/beta / Human/Mouse GSK-3 alpha / beta Alexa Fluor® 700-conjugated Antibody

Human/Mouse GSK-3 alpha / beta Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB25063N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB25063N-100UG

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Human/Mouse GSK-3 alpha / beta Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human GSK-3 beta in direct ELISAs and human GSK-3 alpha and GSK-3 beta in Western blots. Detects human and mouse GSK-3 alpha / beta in immunocytochemistry.
Source
Monoclonal Mouse IgG2b Clone # 833916
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human GSK-3β
Asp200-Phe305
Accession # P49841
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GSK-3 alpha/beta

Glycogen Synthase Kinase-3 (GSK-3) is a serine/threonine kinase initially identified as an inhibitor of glycogen synthase. Two isoforms (GSK-3 alpha and GSK-3 beta ) share 85% amino acid identity. GSK-3 beta, inhibited by phosphorylation at S9 by Akt, is involved in energy metabolism, body pattern formation, and neuronal cell development.

Long Name
Glycogen Synthase Kinase 3
Alternate Names
DKFZp686D0638; EC 2.7.11; EC 2.7.11.26; glycogen synthase kinase 3 alpha; glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK-3 alpha/beta

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