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Human/Mouse PSMB7 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB7590R Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB7590R-100UG

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Human/Mouse PSMB7 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human PSMB7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human PSMB10 is observed.
Source
Monoclonal Mouse IgG1 Clone # 787807
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human PSMB7
Thr44-Ser277
Accession # Q99436
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PSMB7

PSMB7 (proteasome subunit, beta-type 7), also called proteasome subunit Z, is a widely expressed, non-catalytic component of the 20S proteasome core within the 26S proteasome that stabilizes late stages of proteasome assembly. Human PSMB7 is synthesized as a 277 amino acid (aa) protein with a 43 aa propeptide and a 234 active protein that contains one potential tyrosine phosphorylation site. Active human PSMB7 shares 97% aa sequence identity with mouse and rat PSMB7. Total PSMB7 expression is positively correlated with chemotherapy resistance in human breast cancer.

Long Name
Proteasome (Prosome, Macropain) Subunit, beta Type, 7
Entrez Gene IDs
5695 (Human); 19177 (Mouse); 85492 (Rat)
Alternate Names
Macropain Chain Z; Proteasome Subunit Z; PSMB7; Z

Product Datasheets

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