Oligodendrocytes are myelinating cells in the central nervous system (CNS) and form the myelin sheath of axons to support rapid nerve conduction. Oligodendrocyte Marker O4 is an antigen on the surface of oligodendrocyte progenitors (1, 2). It has been commonly used as the earliest recognized marker specific for the oligodendroglial lineage (3-8).
Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 PE‑conjugated Antibody
R&D Systems | Catalog # FAB1326P
Key Product Details
Species Reactivity
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Label
Antibody Source
Product Specifications
Immunogen
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Host
Isotype
Scientific Data Images
Detection of Oligodendrocyte Marker O4 in Rat Cortical Stem Cells by Flow Cytometry.
Rat cortical stem cells either differentiated (filled histogram) or undifferentiated (open histogram) were stained with Mouse Anti-Human/Mouse/Rat/ Chicken Oligodendrocyte Marker O4 PE‑conjugated Monoclonal Antibody (Catalog # FAB1326P). View our protocol for Staining Membrane-associated Proteins.Applications
Flow Cytometry
Sample: Differentiated rat cortical stem cells
Spectra Viewer
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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Formulation
Shipping
Stability & Storage
Background: Oligodendrocyte Marker O4
References
- Schachner, M. et al. (1981) Dev. Biol. 83:328.
- Bansal, R. et al. (1989) J. Neurosci. Res. 24:548.
- Bansal, R. and Pfeiffer, S.E. (1989) Proc. Natl. Acad. Sci. USA 86:6181.
- Gard, A. et al. (1995) Dev. Biol. 167:596.
- Reynolds, R. and Hardy, R. (1997) J. Neurosci. Res. 47:455.
- Ono, K. et al. (1997) J. Neurosci. Res. 48:212.
- Pang, Y. et al. (2000) J. Neurosci. Res. 62:510.
- Cai, Z. et al. (2001) Brain Res. 898:126.
Additional Oligodendrocyte Marker O4 Products
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Product Specific Notices
For research use only
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Citations for Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 PE‑conjugated Antibody
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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