Oligodendrocytes are myelinating cells in the central nervous system (CNS) and form the myelin sheath of axons to support rapid nerve conduction. Oligodendrocyte Marker O4 is an antigen on the surface of oligodendrocyte progenitors (1, 2). It has been commonly used as the earliest recognized marker specific for the oligodendroglial lineage (3-8).
Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Antibody
R&D Systems | Catalog # FAB1326G
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Scientific Data Images for Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Antibody
Detection of Oligodendrocyte Marker O4 in Rat Cortical Stem Cells by Flow Cytometry.
Rat cortical stem cells either differentiated (filled histogram) or undifferentiated (open histogram) were stained with Mouse Anti-Human/Mouse/Rat/ Chicken Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB1326G). View our protocol for Staining Membrane-associated Proteins.
Applications for Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Antibody
Flow Cytometry
Sample: Differentiated Rat Cortical Stem Cells (Catalog # NSC001)
Spectra Viewer
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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Advanced Features
- Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
- Spillover Popups - Visualize the spectra of individual fluorochromes
- Antigen Density Selector - Match fluorochrome brightness with antigen density
Formulation, Preparation, and Storage
Purification
Formulation
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Stability & Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Oligodendrocyte Marker O4
References
- Schachner, M. et al. (1981) Dev. Biol. 83:328.
- Bansal, R. et al. (1989) J. Neurosci. Res. 24:548.
- Bansal, R. and Pfeiffer, S.E. (1989) Proc. Natl. Acad. Sci. USA 86:6181.
- Gard, A. et al. (1995) Dev. Biol. 167:596.
- Reynolds, R. and Hardy, R. (1997) J. Neurosci. Res. 47:455.
- Ono, K. et al. (1997) J. Neurosci. Res. 48:212.
- Pang, Y. et al. (2000) J. Neurosci. Res. 62:510.
- Cai, Z. et al. (2001) Brain Res. 898:126.
Additional Oligodendrocyte Marker O4 Products
Product Documents for Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Antibody
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Product Specific Notices for Oligodendrocyte Marker O4 Alexa Fluor® 488‑conjugated Antibody
This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.
For research use only
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