Human/Mouse/Rat FABP1/L‑FABP Alexa Fluor™ Plus 647‑conjugated Antibody

R&D Systems | Catalog # AF7009AFP647

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Polyclonal Sheep IgG
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Product Specifications

Specificity

Detects human, mouse, and rat FABP1/L-FABP in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications

Application
Recommended Usage

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FABP1/L-FABP

FABP1 (fatty acid binding protein-1; also Liver-type fatty acid binding protein/L-FABP and 14 kDa Selenium-binding protein) is a 14-15 kDa intracellular member of the fatty acid binding protein family, calycin superfamily of molecules. It is expressed by intestinal epithelium and hepatocytes, and is known to bind both cholesterol and long-chain fatty acids in the cytosol. As fatty acids diffuse across the plasma membrane, they are sequestered by FABP1, facilitating fatty acid diffusion into the cell. FABP1 also binds bile acids and cholesterol, and transports cholesterol from one membrane compartment to another. Mouse FABP1 is 127 amino acids (aa) in length. It is a two beta -sheet molecule that contains an acetylated initiating methionine. Full-length mouse FABP1 shares 94% and 84% aa identity with rat and human FABP1, respectively.

Long Name

Fatty Acid-Binding Protein 1

Alternate Names

L-FABP, LFABP

Entrez Gene IDs

2168 (Human); 14080 (Mouse); 24360 (Rat)

Gene Symbol

FABP1

UniProt

Additional FABP1/L-FABP Products

Product Documents

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

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Protocols

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