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Human/Mouse/Rat PBR Polyclonal Ab

Catalog #: 6361-PC-100
2 Citations Datasheet / COA / SDS

Discontinued Product

6361-PC-100 has been discontinued.
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Citations (2)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse/Rat PBR Polyclonal Ab Summary

Species Reactivity
Human, Mouse, Rat
Source
Polyclonal Rabbit IgG
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunohistochemistry
Please refer to the PDF datasheet for specifications.
Immunocytochemistry
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PBR

The peripheral benzodiazepine receptor (PBR) is named for its affinity for benzodiazepines and its initial description in peripheral tissues. This is opposite to the central benzodiazepine receptors (CBRs) of the CNS that are primarily responsible for the relaxant, anticonvulsant, and anxiolytic effects of benzodiazepines. PBR is a transmembrane protein associated with the outer mitochondrial membrane. It has been implicated in several physiological functions, including steroidogenesis, mitochondrial respiratory control, and cell growth, survival, differentiation, and chemotaxis.

Long Name
Peripheral-type Benzodiazepine Receptor
Entrez Gene IDs
706 (Human)
Alternate Names
benzodiazepine peripheral binding site; BZRPDBI; IBP; MBRPBS; mDRC; Mitochondrial benzodiazepine receptor; PBR; PBRBPBS; PBRS; peripheral benzodiazepine receptor; Peripheral-type benzodiazepine receptor; pk18; PKBSbenzodiazapine receptor (peripheral); PTBR; translocator protein (18kDa); translocator protein; TSPO

Product Datasheets

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COA

Citations for Human/Mouse/Rat PBR Polyclonal Ab

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. The upregulation of translocator protein (18 kDa) promotes recovery from neuropathic pain in rats.
    Authors: Wei X, Wei X, Chen F, Zang Y, Xin W, Pang R, Chen Y, Wang J, Li Y, Shen K, Zhou L, Liu X
    J Neurosci, 2013-01-23;33(4):1540-51.
    Species: Rat
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  2. Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands.
    Authors: Falchi AM, Battetta B, Sanna F, Piludu M, Sogos V, Serra M, Melis M, Putzolu M, Diaz G
    Neuropharmacology, 2007-06-02;53(2):318-29.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: ICC

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