Human/Mouse/Rat Zyxin Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Zyxin

Zyxin (ZYX), also known as Zyxin 2, is an approximately 80-85 kDa intracellular protein that functions in the regulation of actin cytoskeleton dynamics. Zyxin plays a role in remodeling of the actin cytoskeleton during wound healing, cell migration, cell adhesion, and epithelial-mesenchymal transition. The N-terminal region of Zyxin is proline-rich, while the C-terminal region contains three tandem LIM zinc-binding domains (aa 384-570). Within aa 265-383, human Zyxin shares 81% and 84% aa sequence identity with mouse and rat Zyxin, respectively.

Product Datasheets

Related Research Areas

• Actin Stress Fibers and Focal Adhesions During EMT
• Adhesion Molecules on Endothelial Cells
• Adhesion Molecules on VSMC
• Contractile Mechanism and Cytoskeleton in VSMC
• Focal Adhesions
• Microfilament-associated Proteins
• Phospholipases, Small GTPases, and Other Molecules in the Akt Pathway