Human MSX1 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB5045G Datasheet / COA / SDS

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FAB5045G-100UG

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Human MSX1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human MSX1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MSX2 is observed.

Source

Monoclonal Mouse IgG2a Clone # 801601

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human MSX1
Met1-Thr165
Accession # P28360

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MSX1

MSX1 (Msh homeobox homology 1) is a member of the muscle segment homoebox gene family. MSX1 is involved in limb-pattern formation, craniofacial development, odontogenesis, and tumor growth inhibition. MSX1 functions as a transcriptional repressor. MSX1 has been shown to interact with the linker histone, H1B, and repress transcription of the MyoD promoter. Chromosomal abnormalities involving MSX1 have been associated with the Wolf-Hirschhorn syndrome characterized by heart defects and mental retardation.

Long Name

Msh Homeobox 1

Entrez Gene IDs

4487 (Human); 17701 (Mouse); 81710 (Rat)

Alternate Names

Homeobox protein Hox-7; homeobox protein MSX-1; HOX7; HOX7homeobox 7; HYD1; HYD1msh homeobox homolog 1 (Drosophila); msh (Drosophila) homeo box homolog 1 (formerly homeo box 7); msh homeo box 1; msh homeobox 1; Msh homeobox 1-like protein; msh homeobox homolog 1; MSX1; OFC5; STHAG1