Human Neurophysin II Alexa Fluor® 700-conjugated Antibody Summary
Accession # P01186
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: Neurophysin II
Arginine vasopressin (AVP)/Neurophysin 2 is a hormone synthesized in neurons in the hypothalamus that specifically binds vasopressin. Vasopressin has a direct antidiuretic action on the kidney and causes vasoconstriction of the peripheral vessels. Vasopressin regulates the tonicity of body fluid by causing the kidneys to reabsorb solute-free water and returning it to the circulation from the tubules of the nephron. AVP released in high concentrations may also raise blood pressure by inducing vasoconstriction. The stimulus for secretion of vasopressin is increased osmolality of the plasma which is monitored by the hypothalamus. Vasopressin is often used to manage anti-diuretic hormone deficiency.
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