Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)

R&D Systems | Catalog # PP-N1404-00

R&D Systems
Discontinued Product
PP-N1404-00 has been discontinued. An alternative/replacement product is available: PP-N1404-0C. View all Nurr1/NGFI-B beta/NR4A2 products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Rat

Applications

Validated:

Immunohistochemistry, Western Blot, Immunoprecipitation

Cited:

Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # N1404
View all Nurr1/NGFI-B beta/NR4A2 Primary Antibodies »

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Perfusion fixed paraffin-embedded sections of rat cerebral nerve cells

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using PP-N1404-00 in the following applications:

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Nurr1/NGFI-B beta/NR4A2

Nurr1 belongs to the nerve growth factor-induced clone B subfamily of nuclear receptor superfamily and is designated NR4A2 in the Unified Nomenclature System for NRs. Nurr1 can function as a ligand-independent transcription factor. Nurr1 also heterodimerizes with retinoid X receptors (RXRs) to function as ligand-regulated transcription factor. Nurr 1 is important for specification of dopaminergic neurons that degenerate in Parkinsons disease. Human and mouse Nurr1 share 99% amino acid sequence homology.

Long Name

Nur-related Factor 1/Nerve Growth Factor Induced B beta/Nuclear Receptor Subfamily 4, Group A, 2

Alternate Names

NGFI-B beta, NOT, NR4A2, TINUR

Entrez Gene IDs

4929 (Human); 18227 (Mouse)

Gene Symbol

NR4A2

Additional Nurr1/NGFI-B beta/NR4A2 Products

Product Documents for Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)

For research use only

Citations for Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)

Customer Reviews for Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404) (1)

5 out of 5
1 Customer Rating
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 of 1 review Showing All
Filter By:
Clear Filters X
  • Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404)
    Name: Anonymous
    Application: Immunohistochemistry
    Sample Tested: Kidney tissue
    Species: Human
    Verified Customer | Posted 02/09/2022
    Human Nurr1/NGFI-B beta/NR4A2 MAb (Clone N1404) PP-N1404-00

There are no reviews that match your criteria.

Showing  1 - 1 of 1 review Showing All

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies