Human p300 ExactaChIP Chromatin IP Kit

Name: Human p300 ExactaChIP Chromatin IP Kit
Brand: R&D Systems
SKU: ECP3789

Catalog #: ECP3789 Datasheet / COA / SDS

Discontinued Product

ECP3789 has been discontinued.

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Summary Product Datasheets Background

Human p300 ExactaChIP Chromatin IP Kit Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: p300

The E1A-binding protein p300 is a histone acetyltransferase that also acts to acetylate other proteins, such as p53. p300 acts as a transcriptional coactivator that can serve as an adaptor molecule to bridge to transcriptional regulators. In addition, p300 binds to PCNA and may participate in chromatin remodeling.

The large p300 protein associates with CREB-binding protein(CBP) in numerous types of cells, forming the p300/CBP transcription co-activator that regulates gene expression by promoting acetylation of histones and other transcription factors, most notably p53. Dysregulation of the p300/CBP complex has been related to several types of human cancers.

Long Name

E1A-binding Protein p300

Entrez Gene IDs

2033 (Human); 328572 (Mouse)

Alternate Names

E1A binding protein p300; E1A-associated protein p300; E1A-binding protein, 300kD; EC 2.3.1; EC 2.3.1.48; EP300; histone acetyltransferase p300; KAT3B; p300 HAT; p300; RSTS2