Human PILR-beta Antibody [Biotin]

R&D Systems | Catalog # BAF4189

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG
View all PILR-beta Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human PILR-beta isoform 1
Gln20-Ala189
Accession # Q9UKJ0

Specificity

Detects human PILR-beta in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human PILR-alpha is observed and less than 5% cross-reactivity with recombinant mouse PILR-beta, rmPILR-alpha, and rmPILR-L is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human PILR-beta Antibody [Biotin]

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human PILR-beta

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: PILR-beta

Paired immunoglobulin-like, type 2 receptor beta (PILR-beta ) is a type I transmembrane (TM) glycoprotein belonging to the Ig superfamily. It is the activating counterpart to the ITIM-bearing PILR-alpha inhibitory receptor. PILR-beta is expressed in a wide variety of tissues including hematopoietic cells. Mature human PILR-beta is a 208 amino acid (aa) protein with one V-type Ig-like extracellular domain, a truncated cytoplasmic tail, and positively-charged residues in its TM domain that interacts with ITAM‑bearing adaptor molecules. Within the V-type Ig-like region in their ECD, human PILR-beta and PILR-alpha share a 92% aa sequence identity. The aa sequence of mouse PILR-beta ECD is only 43% identical to that of the human protein.

Long Name

Paired-Ig-likeType 2 Receptor beta

Alternate Names

FDFACT1, FDFACT2, PILRB, PILRbeta

Entrez Gene IDs

29990 (Human); 170741 (Mouse)

Gene Symbol

PILRB

UniProt

Q9UKJ0

Additional PILR-beta Products

Product Documents for Human PILR-beta Antibody [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human PILR-beta Antibody [Biotin]

For research use only

Related Research Areas

Dendritic Cell Activation

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