Human PP2C gamma Alexa Fluor® 647-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB5595R-100UG

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Human PP2C gamma Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human PP2C gamma.
Source
Monoclonal Mouse IgG1 Clone # 528322
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human PP2Cγ
Met1-Asp546
Accession # O15355
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PP2C gamma

Protein phosphatase 2C isoform gamma (PP2C gamma; also PPM1G) is a widely expressed, 75 kDa member of the PP2C family of Ser/Thr protein phosphatases. Human PP2C gamma is 546 amino acids (aa) in length. The apparent mass is much larger than the predicted mass of 59 kDa because of the presence of an acidic region (aa 259‑326) rich in glutamate and aspartate residues, causing the protein to move anomalously on SDS-PAGE. The protein contains numerous sites for phosphorylation by casein kinase II, particularly within the acidic domain.

Long Name
Protein Phosphatase 2C gamma
Entrez Gene IDs
5496 (Human); 14208 (Mouse); 259229 (Rat)
Alternate Names
EC 3.1.3.16; MGC1675; MGC2870; PP2C gamma; PP2C, gamma; PP2CG; PP2CGAMMA; PP2C-gamma; PPM1C; PPM1G; PPP2CG; Protein phosphatase 1C; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 1G; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; protein phosphatase, Mg2+/Mn2+ dependent, 1G

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