PTGIR is a member of the G protein-coupled receptor family 1 and has been shown to be a receptor for prostacyclin (prostaglandin I2 or PGI2). Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to PTGIR.
Human PTGIR (NP_000951) VersaClone cDNA
R&D Systems | Catalog # RDC0268
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PTGIR
Long Name
Prostaglandin I2 Receptor
Alternate Names
IP, PRIPR
Gene Symbol
PTGIR
UniProt
Additional PTGIR Products
Product Documents for Human PTGIR (NP_000951) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human PTGIR (NP_000951) VersaClone cDNA
For research use only
Related Research Areas
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